Quantitative histological analysis of the cerebellar cortex in the cat. II. Cell numbers and densities in the granular layer

M. Palkovits, P. Magyar, J. Szentágothai

Research output: Contribution to journalArticle

92 Citations (Scopus)

Abstract

Numbers and densities of different cell types have been studied in the granular layer of the cerebellar cortex in the adult cat with the aid of various quantitative histological methods. A percentage of 41.85% of the total volume of the granular substance was occupied by the granule cells (bodies), their density calculated for the living state being 2.8 · 106/cu.mm. The granular contributed to 29.09% of the total cerebellar volume, their absolute number being 2.2 · 109. The granule cell: Purkinje cell ratio was 1700-1800 : 1. In flat regions of the folium the density of granule axons ascending through the ganglionic layer was 687.016/sq.mm, calculated for the living cat. The density of Golgi cells determined by two entirely different approaches was 980 and 1092/cu.mm respectively. Eighthy-nine per cent of the Golgi cells: localized in the outer half of the granular layer. The numerical ration of Golgi cells: Purkinje cells was 1 : 3. This density of the Golgi cells - assuming non-overlap between dendrites and axons - would require a compartmentation of the space available to the Golgi cells in an idealized model into hexagonal prisms of around 100 μm diamter. The prisms would cut vertically through all 3 layers of the cortex, and the volume of the part corresponding to the granular layer would be approximately 0.002 cu.mm (calculated for the living cat), containing about 200 glomeruli.

Original languageEnglish
Pages (from-to)15-30
Number of pages16
JournalBrain research
Volume32
Issue number1
DOIs
Publication statusPublished - Sep 10 1971

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Fingerprint Dive into the research topics of 'Quantitative histological analysis of the cerebellar cortex in the cat. II. Cell numbers and densities in the granular layer'. Together they form a unique fingerprint.

  • Cite this