Quantitative estimation of film forming polymer-plasticizer interactions by the Lorentz-Lorenz Law

J. Dredán, R. Zelkó, Á Z. Dávid, I. Antal

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Molar refraction as well as refractive index has many uses. Beyond confirming the identity and purity of a compound, determination of molecular structure and molecular weight, molar refraction is also used in other estimation schemes, such as in critical properties, surface tension, solubility parameter, molecular polarizability, dipole moment, etc. In the present study molar refraction values of polymer dispersions were determined for the quantitative estimation of film forming polymer-plasticizer interactions. Information can be obtained concerning the extent of interaction between the polymer and the plasticizer from the calculation of molar refraction values of film forming polymer dispersions containing plasticizer.

Original languageEnglish
Pages (from-to)25-30
Number of pages6
JournalInternational Journal of Pharmaceutics
Volume310
Issue number1-2
DOIs
Publication statusPublished - Mar 9 2006

Keywords

  • Film coating
  • Molar refraction
  • Polymer-plasticizer interaction

ASJC Scopus subject areas

  • Pharmaceutical Science

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