Quantitative electron microscopy of the cerebellar molecular layer in corticopontocerebellar atrophy

R. Uzunova, J. Hámori

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Cortico ponto cerebellar atrophy of the cerebellar cortex, which causes a dramatic numerical reduction in the development of postsynaptic dendritic digits in the cerebellar glomeruli, does not affect the number of developing Purkinje cell dendritic spines. The spines, however, in the atrophic cerebellar cortex are much smaller than the normal spines. It is suggested, therefore, that though the development of the dendritic spines per se is not affected by the (presumably functionally altered) presynaptic parallel fibers, the final size and shape of the postsynaptic spines is dependent on the normal functioning of the synapsing parallel axons.

Original languageEnglish
Pages (from-to)117-122
Number of pages6
JournalActa Biologica Academiae Scientiarum Hungaricae
Volume25
Issue number1-2
Publication statusPublished - 1974

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electron microscopy
atrophy
Electron microscopy
Atrophy
Electron Microscopy
Dendritic Spines
cortex
Cerebellar Cortex
Spine
Fibers
dendritic cells
axons
Purkinje Cells
Axons
Dendritic Cells
fibre

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Quantitative electron microscopy of the cerebellar molecular layer in corticopontocerebellar atrophy. / Uzunova, R.; Hámori, J.

In: Acta Biologica Academiae Scientiarum Hungaricae, Vol. 25, No. 1-2, 1974, p. 117-122.

Research output: Contribution to journalArticle

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