Quantitation of macrophage activation.

S. I. Vas, G. A. Nicoll

Research output: Contribution to journalArticle


Chemoluminescence is a sensitive and relatively easy method to quantitate macrophage activation. Cytotoxic assay as measured by 51Cr release from tumour target cells is more involved and less sensitive. Our experiments indicate that, depending on the mode of activation, different effector mechanisms are operational. Thus, macrophages activated with double stranded yeast RNA show good chemoluminescence but no cytotoxic response while thioglycollate activated macrophages show the reverse response.

Original languageEnglish
Pages (from-to)217-226
Number of pages10
JournalActa microbiologica Hungarica
Issue number3-4
Publication statusPublished - Dec 1 1983


ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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