Quality of life and protein-energy wasting in kidney transplant recipients

Akos Ujszaszi, Maria E. Czira, Katalin Fornadi, M. Novák, I. Mucsi, M. Molnár

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Purpose Chronic kidney disease has profound effects on the health-related quality of life (HRQoL) of patients, with serious physiological, psychological and socio-economic implications. The co-occurrence of protein-energy wasting and inflammation in endstage renal disease patients is associated with worse HRQoL and increased mortality. We designed this study to examine the relationship between nutritional and inflammatory status and HRQoL in kidney transplant recipients. Methods: Data from 100 randomly selected kidney transplant patients were analyzed in a cross-sectional survey. Socio-demographic parameters, laboratory results, transplantation-related data, comorbidities, medication and malnutrition-inflammation score (MIS) (Kalantar Score) were tabulated at baseline. Patients completed the Kidney Disease Quality of Life- SF (KDQoL-SF™) self-administered questionnaire. Results: Mean age was 51 ± 13 years, median (interquartile range, IQR) time since transplantation 66 (83) months, 57% were men, and 19% had diabetes. The median (IQR)MIS was 3 (3). TheMIS significantly and negatively correlated with almost all HRQoL domains analyzed, and this association remained significant in multivariate linear regression analysis for log-transformed scores on energy/fatigue (β = -0.059 P

Original languageEnglish
Pages (from-to)1257-1268
Number of pages12
JournalInternational Urology and Nephrology
Volume44
Issue number4
DOIs
Publication statusPublished - Aug 2012

Fingerprint

Quality of Life
Kidney
Inflammation
Proteins
Malnutrition
Transplantation
Kidney Diseases
Nutritional Status
Chronic Renal Insufficiency
Fatigue
Comorbidity
Linear Models
Cross-Sectional Studies
Regression Analysis
Economics
Demography
Transplant Recipients
Psychology
Transplants
Mortality

Keywords

  • Kidney transplantation
  • Malnutrition-inflammation score
  • Protein-energy wasting
  • Quality of life

ASJC Scopus subject areas

  • Nephrology
  • Urology

Cite this

Quality of life and protein-energy wasting in kidney transplant recipients. / Ujszaszi, Akos; Czira, Maria E.; Fornadi, Katalin; Novák, M.; Mucsi, I.; Molnár, M.

In: International Urology and Nephrology, Vol. 44, No. 4, 08.2012, p. 1257-1268.

Research output: Contribution to journalArticle

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