Pycnogenol a klinikai gyakorlatban

Translated title of the contribution: Pycnogenol in the clinical practice

Kiss István, Tavaszy Mariann, C. Farsang

Research output: Contribution to journalArticle

Abstract

Polyphenols, which belong to the group of flavonoids, can be found in a number of plants, and are present in a high concentration in the French maritime pine bark. The authors summarise results of large-scale experimental and clinical studies on pycnogenol, the standardised extract of French maritime pine bark. Pycnogenol decreases production and effects of free radicals (antioxidant effect). It has antiinflammatory properties, and, by the stimulation of eNOS-synthesis, it increases the production of vasodilatory compounds (e.g. NO, prostacyclin) and decreases that of vascoconstrictor compounds (endothelin-1, thromboxane) materials. These changes lead to vasodilation, which results in increased tissue perfusion and decreased blood pressure. Pycnogenol also decreases platelet aggregation and LDL-cholesterol level and increases HDL-cholesterol level. Its antidiabetic effect has also been shown. Consequently, it may substantially decrease cardiovascular risk. In addition to these results, pycnogenol has been also found to have antibacterial and antiviral effects. It has been successfully used in children with attention deficit hyperactivity disorder, as well as in adults with dysmenorrhea, climacterial disturbances, glaucoma or asthma bronchiale.

Original languageHungarian
Pages (from-to)621-626
Number of pages6
JournalLege Artis Medicinae
Volume21
Issue number10
Publication statusPublished - Oct 2011

Fingerprint

Pinus
Dysmenorrhea
Thromboxanes
Polyphenols
Endothelin-1
Epoprostenol
Attention Deficit Disorder with Hyperactivity
Platelet Aggregation
Hypoglycemic Agents
Flavonoids
Vasodilation
Glaucoma
LDL Cholesterol
HDL Cholesterol
Free Radicals
Antiviral Agents
Anti-Inflammatory Agents
Asthma
Perfusion
Antioxidants

ASJC Scopus subject areas

  • Medicine(all)

Cite this

István, K., Mariann, T., & Farsang, C. (2011). Pycnogenol a klinikai gyakorlatban. Lege Artis Medicinae, 21(10), 621-626.

Pycnogenol a klinikai gyakorlatban. / István, Kiss; Mariann, Tavaszy; Farsang, C.

In: Lege Artis Medicinae, Vol. 21, No. 10, 10.2011, p. 621-626.

Research output: Contribution to journalArticle

István, K, Mariann, T & Farsang, C 2011, 'Pycnogenol a klinikai gyakorlatban', Lege Artis Medicinae, vol. 21, no. 10, pp. 621-626.
István K, Mariann T, Farsang C. Pycnogenol a klinikai gyakorlatban. Lege Artis Medicinae. 2011 Oct;21(10):621-626.
István, Kiss ; Mariann, Tavaszy ; Farsang, C. / Pycnogenol a klinikai gyakorlatban. In: Lege Artis Medicinae. 2011 ; Vol. 21, No. 10. pp. 621-626.
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