PURPURA CRYOMACROGLOBULINAEMICA BEI MIT LEBERZIRRHOSE EINHERGHENDER HEPATISCHER PORPHYRIE

Translated title of the contribution: Purpura kryomacroglobulinemica with liver cirrhosis and hepatic porphyria

N. Simon, S. Husz, J. Masszi

Research output: Contribution to journalArticle

Abstract

Hepatic porphyria and histologically verified cirrhosis, teleangiectasia, purpose, papular skin lesions existing for 8 yr, as well as cryomacroglobulin were found in a 49 yr old man. Pathogenetically the liver disease is considered to be the primary event, which was accompanied by secondary cryoglobulinemia. IgG and IgM type of thrombus in the vessels and of small granular deposits corresponding to the type of cryoprotein in the blood, were detected in the vessel walls of the upper part in the dermis and along these vessels of both purpuri and papular skin lesions. Immunoprecipitates could be revealed by FTC-labelled antihuman complement. In the skin lesions porphyrin could not be demonstrated. The investigation of cryoglobulin and of porphyrin disorders is reasonable in every patient with purpura accompanying pathological liver processes.

Original languageGerman
Pages (from-to)303-307
Number of pages5
JournalHautarzt
Volume28
Issue number6
Publication statusPublished - Dec 1 1977

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ASJC Scopus subject areas

  • Dermatology

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