Psychological rejection of the transplanted organ and graft dysfunction in kidney transplant patients

Melinda Látos, György Lázár, Zoltán Horváth, Victoria Wittmann, Edit Szederkényi, Zoltán Hódi, P. Szenohradszky, Márta Csabai

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Interdisciplinary studies suggest that the mental representations of the transplanted organ may have a significant effect on the healing process. The objective of this study was to examine the representations of the transplanted organ and their relationship with emotional and mood factors, illness perceptions, and the functioning of the transplanted organ. One hundred and sixty-four kidney transplant patients were assessed using the Spielberger Anxiety Inventory, the Beck’s Depression Scale, the Posttraumatic Growth Inventory, the Brief Illness Perception Questionnaire, and the Transplanted Organ Questionnaire. Medical parameters were collected from the routine clinical blood tests (serum creatinine and estimated glomerular filtration rate levels) and biopsy results. Our most outstanding results suggest that kidney-transplanted patients’ illness representations are associated with health outcomes. The Transplanted Organ Questionnaire “psychological rejection” subscale was connected with higher serum creatinine and estimated glomerular filtration rate levels. Logistic regression analysis showed that psychological rejection subscale, Brief Illness Perception Questionnaire, and Posttraumatic Growth Questionnaire total scores were associated with graft rejection. These results may serve as a basis for the development of complex treatment interventions, which could help patients to cope with the bio-psycho-social challenges of integrating the new organ as part of their body and self.

Original languageEnglish
Pages (from-to)15-24
Number of pages10
JournalTransplant Research and Risk Management
Volume8
DOIs
Publication statusPublished - Jun 29 2016

Fingerprint

Kidney
Rejection
Questionnaire
Psychology
Transplants
Glomerular Filtration Rate
Filtration
Creatinine
Interdisciplinary Studies
Equipment and Supplies
Mood
Anxiety
Graft Rejection
Hematologic Tests
Growth
Logistic Regression
Serum
Human Body
Regression Analysis
Blood

Keywords

  • Anxiety
  • Depression
  • Illness representations
  • Posttraumatic growth
  • Psychological rejection
  • Renal transplantation

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Transplantation

Cite this

Látos, M., Lázár, G., Horváth, Z., Wittmann, V., Szederkényi, E., Hódi, Z., ... Csabai, M. (2016). Psychological rejection of the transplanted organ and graft dysfunction in kidney transplant patients. Transplant Research and Risk Management, 8, 15-24. https://doi.org/10.2147/TRRM.S104133

Psychological rejection of the transplanted organ and graft dysfunction in kidney transplant patients. / Látos, Melinda; Lázár, György; Horváth, Zoltán; Wittmann, Victoria; Szederkényi, Edit; Hódi, Zoltán; Szenohradszky, P.; Csabai, Márta.

In: Transplant Research and Risk Management, Vol. 8, 29.06.2016, p. 15-24.

Research output: Contribution to journalArticle

Látos, Melinda ; Lázár, György ; Horváth, Zoltán ; Wittmann, Victoria ; Szederkényi, Edit ; Hódi, Zoltán ; Szenohradszky, P. ; Csabai, Márta. / Psychological rejection of the transplanted organ and graft dysfunction in kidney transplant patients. In: Transplant Research and Risk Management. 2016 ; Vol. 8. pp. 15-24.
@article{151760d6cb554a618f4d2abfa4f7afe4,
title = "Psychological rejection of the transplanted organ and graft dysfunction in kidney transplant patients",
abstract = "Interdisciplinary studies suggest that the mental representations of the transplanted organ may have a significant effect on the healing process. The objective of this study was to examine the representations of the transplanted organ and their relationship with emotional and mood factors, illness perceptions, and the functioning of the transplanted organ. One hundred and sixty-four kidney transplant patients were assessed using the Spielberger Anxiety Inventory, the Beck’s Depression Scale, the Posttraumatic Growth Inventory, the Brief Illness Perception Questionnaire, and the Transplanted Organ Questionnaire. Medical parameters were collected from the routine clinical blood tests (serum creatinine and estimated glomerular filtration rate levels) and biopsy results. Our most outstanding results suggest that kidney-transplanted patients’ illness representations are associated with health outcomes. The Transplanted Organ Questionnaire “psychological rejection” subscale was connected with higher serum creatinine and estimated glomerular filtration rate levels. Logistic regression analysis showed that psychological rejection subscale, Brief Illness Perception Questionnaire, and Posttraumatic Growth Questionnaire total scores were associated with graft rejection. These results may serve as a basis for the development of complex treatment interventions, which could help patients to cope with the bio-psycho-social challenges of integrating the new organ as part of their body and self.",
keywords = "Anxiety, Depression, Illness representations, Posttraumatic growth, Psychological rejection, Renal transplantation",
author = "Melinda L{\'a}tos and Gy{\"o}rgy L{\'a}z{\'a}r and Zolt{\'a}n Horv{\'a}th and Victoria Wittmann and Edit Szederk{\'e}nyi and Zolt{\'a}n H{\'o}di and P. Szenohradszky and M{\'a}rta Csabai",
year = "2016",
month = "6",
day = "29",
doi = "10.2147/TRRM.S104133",
language = "English",
volume = "8",
pages = "15--24",
journal = "Transplant Research and Risk Management",
issn = "1179-1616",
publisher = "Dove Medical Press Ltd.",

}

TY - JOUR

T1 - Psychological rejection of the transplanted organ and graft dysfunction in kidney transplant patients

AU - Látos, Melinda

AU - Lázár, György

AU - Horváth, Zoltán

AU - Wittmann, Victoria

AU - Szederkényi, Edit

AU - Hódi, Zoltán

AU - Szenohradszky, P.

AU - Csabai, Márta

PY - 2016/6/29

Y1 - 2016/6/29

N2 - Interdisciplinary studies suggest that the mental representations of the transplanted organ may have a significant effect on the healing process. The objective of this study was to examine the representations of the transplanted organ and their relationship with emotional and mood factors, illness perceptions, and the functioning of the transplanted organ. One hundred and sixty-four kidney transplant patients were assessed using the Spielberger Anxiety Inventory, the Beck’s Depression Scale, the Posttraumatic Growth Inventory, the Brief Illness Perception Questionnaire, and the Transplanted Organ Questionnaire. Medical parameters were collected from the routine clinical blood tests (serum creatinine and estimated glomerular filtration rate levels) and biopsy results. Our most outstanding results suggest that kidney-transplanted patients’ illness representations are associated with health outcomes. The Transplanted Organ Questionnaire “psychological rejection” subscale was connected with higher serum creatinine and estimated glomerular filtration rate levels. Logistic regression analysis showed that psychological rejection subscale, Brief Illness Perception Questionnaire, and Posttraumatic Growth Questionnaire total scores were associated with graft rejection. These results may serve as a basis for the development of complex treatment interventions, which could help patients to cope with the bio-psycho-social challenges of integrating the new organ as part of their body and self.

AB - Interdisciplinary studies suggest that the mental representations of the transplanted organ may have a significant effect on the healing process. The objective of this study was to examine the representations of the transplanted organ and their relationship with emotional and mood factors, illness perceptions, and the functioning of the transplanted organ. One hundred and sixty-four kidney transplant patients were assessed using the Spielberger Anxiety Inventory, the Beck’s Depression Scale, the Posttraumatic Growth Inventory, the Brief Illness Perception Questionnaire, and the Transplanted Organ Questionnaire. Medical parameters were collected from the routine clinical blood tests (serum creatinine and estimated glomerular filtration rate levels) and biopsy results. Our most outstanding results suggest that kidney-transplanted patients’ illness representations are associated with health outcomes. The Transplanted Organ Questionnaire “psychological rejection” subscale was connected with higher serum creatinine and estimated glomerular filtration rate levels. Logistic regression analysis showed that psychological rejection subscale, Brief Illness Perception Questionnaire, and Posttraumatic Growth Questionnaire total scores were associated with graft rejection. These results may serve as a basis for the development of complex treatment interventions, which could help patients to cope with the bio-psycho-social challenges of integrating the new organ as part of their body and self.

KW - Anxiety

KW - Depression

KW - Illness representations

KW - Posttraumatic growth

KW - Psychological rejection

KW - Renal transplantation

UR - http://www.scopus.com/inward/record.url?scp=84987923143&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84987923143&partnerID=8YFLogxK

U2 - 10.2147/TRRM.S104133

DO - 10.2147/TRRM.S104133

M3 - Article

VL - 8

SP - 15

EP - 24

JO - Transplant Research and Risk Management

JF - Transplant Research and Risk Management

SN - 1179-1616

ER -