Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: Results of the IASP study

Katelijne Van Emmerik-van Oortmerssen, Geurt van de Glind, Maarten W J Koeter, Steve Allsop, Marc Auriacombe, C. Barta, Eli Torild H Bu, Yuliya Burren, Pieter Jan Carpentier, Susan Carruthers, Miguel Casas, Z. Demetrovics, Geert Dom, Stephen V. Faraone, Melina Fatseas, Johan Franck, Brian Johnson, Máté Kapitány-Fövény, Sharlene Kaye, Maija KonsteniusFrances R. Levin, Franz Moggi, Merete Møller, J. Antoni Ramos-Quiroga, Arild Schillinger, Arvid Skutle, Sofie Verspreet, Wim van den Brink, Robert A. Schoevers, Atul Beniwal, Geert Bosma, Joanne Cassar, Therese Dahl, Constanza Daigre, Romain Debrabant, Louisa Degenhardt, Rutger Jan van der Gaag, David Hay, Kari Lossius, Eva Karin Løvaas, Marion Malivert, Merete Möller, Carlos Roncero, Laura Stevens, Sara Wallhed, Anneke van Wamel, Jesse Young

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Aims: To determine comorbidity patterns in treatment-seeking substance use disorder (SUD) patients with and without adult attention deficit hyperactivity disorder (ADHD), with an emphasis on subgroups defined by ADHD subtype, taking into account differences related to gender and primary substance of abuse. Design: Data were obtained from the cross-sectional International ADHD in Substance use disorder Prevalence (IASP) study. Setting: Forty-seven centres of SUD treatment in 10 countries. Participants: A total of 1205 treatment-seeking SUD patients. Measurements: Structured diagnostic assessments were used for all disorders: presence of ADHD was assessed with the Conners' Adult ADHD Diagnostic Interview for DSM-IV (CAADID), the presence of antisocial personality disorder (ASPD), major depression (MD) and (hypo)manic episode (HME) was assessed with the Mini International Neuropsychiatric Interview-Plus (MINI Plus), and the presence of borderline personality disorder (BPD) was assessed with the Structured Clinical Interview for DSM-IV Axis II (SCID II). Findings: The prevalence of DSM-IV adult ADHD in this SUD sample was 13.9%. ASPD [odds ratio (OR)=2.8, 95% confidence interval (CI)=1.8-4.2], BPD (OR=7.0, 95% CI=3.1-15.6 for alcohol; OR=3.4, 95% CI=1.8-6.4 for drugs), MD in patients with alcohol as primary substance of abuse (OR=4.1, 95% CI=2.1-7.8) and HME (OR=4.3, 95% CI=2.1-8.7) were all more prevalent in ADHD+ compared with ADHD- patients (P

Original languageEnglish
Pages (from-to)262-272
Number of pages11
JournalAddiction
Volume109
Issue number2
DOIs
Publication statusPublished - Feb 2014

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Attention Deficit Disorder with Hyperactivity
Substance-Related Disorders
Psychiatry
Comorbidity
Cross-Sectional Studies
Odds Ratio
Confidence Intervals
Diagnostic and Statistical Manual of Mental Disorders
Antisocial Personality Disorder
Borderline Personality Disorder
Interviews
Therapeutics
Alcohols
Depression
Pharmaceutical Preparations

Keywords

  • ADHD
  • Antisocial personality disorder
  • Bipolar disorder
  • Borderline personality disorder
  • Comorbidity
  • Depression
  • Substance use disorder

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Psychiatry and Mental health
  • Medicine(all)

Cite this

Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder : Results of the IASP study. / Van Emmerik-van Oortmerssen, Katelijne; van de Glind, Geurt; Koeter, Maarten W J; Allsop, Steve; Auriacombe, Marc; Barta, C.; Bu, Eli Torild H; Burren, Yuliya; Carpentier, Pieter Jan; Carruthers, Susan; Casas, Miguel; Demetrovics, Z.; Dom, Geert; Faraone, Stephen V.; Fatseas, Melina; Franck, Johan; Johnson, Brian; Kapitány-Fövény, Máté; Kaye, Sharlene; Konstenius, Maija; Levin, Frances R.; Moggi, Franz; Møller, Merete; Ramos-Quiroga, J. Antoni; Schillinger, Arild; Skutle, Arvid; Verspreet, Sofie; van den Brink, Wim; Schoevers, Robert A.; Beniwal, Atul; Bosma, Geert; Cassar, Joanne; Dahl, Therese; Daigre, Constanza; Debrabant, Romain; Degenhardt, Louisa; van der Gaag, Rutger Jan; Hay, David; Lossius, Kari; Løvaas, Eva Karin; Malivert, Marion; Möller, Merete; Roncero, Carlos; Stevens, Laura; Wallhed, Sara; van Wamel, Anneke; Young, Jesse.

In: Addiction, Vol. 109, No. 2, 02.2014, p. 262-272.

Research output: Contribution to journalArticle

Van Emmerik-van Oortmerssen, K, van de Glind, G, Koeter, MWJ, Allsop, S, Auriacombe, M, Barta, C, Bu, ETH, Burren, Y, Carpentier, PJ, Carruthers, S, Casas, M, Demetrovics, Z, Dom, G, Faraone, SV, Fatseas, M, Franck, J, Johnson, B, Kapitány-Fövény, M, Kaye, S, Konstenius, M, Levin, FR, Moggi, F, Møller, M, Ramos-Quiroga, JA, Schillinger, A, Skutle, A, Verspreet, S, van den Brink, W, Schoevers, RA, Beniwal, A, Bosma, G, Cassar, J, Dahl, T, Daigre, C, Debrabant, R, Degenhardt, L, van der Gaag, RJ, Hay, D, Lossius, K, Løvaas, EK, Malivert, M, Möller, M, Roncero, C, Stevens, L, Wallhed, S, van Wamel, A & Young, J 2014, 'Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: Results of the IASP study', Addiction, vol. 109, no. 2, pp. 262-272. https://doi.org/10.1111/add.12370
Van Emmerik-van Oortmerssen, Katelijne ; van de Glind, Geurt ; Koeter, Maarten W J ; Allsop, Steve ; Auriacombe, Marc ; Barta, C. ; Bu, Eli Torild H ; Burren, Yuliya ; Carpentier, Pieter Jan ; Carruthers, Susan ; Casas, Miguel ; Demetrovics, Z. ; Dom, Geert ; Faraone, Stephen V. ; Fatseas, Melina ; Franck, Johan ; Johnson, Brian ; Kapitány-Fövény, Máté ; Kaye, Sharlene ; Konstenius, Maija ; Levin, Frances R. ; Moggi, Franz ; Møller, Merete ; Ramos-Quiroga, J. Antoni ; Schillinger, Arild ; Skutle, Arvid ; Verspreet, Sofie ; van den Brink, Wim ; Schoevers, Robert A. ; Beniwal, Atul ; Bosma, Geert ; Cassar, Joanne ; Dahl, Therese ; Daigre, Constanza ; Debrabant, Romain ; Degenhardt, Louisa ; van der Gaag, Rutger Jan ; Hay, David ; Lossius, Kari ; Løvaas, Eva Karin ; Malivert, Marion ; Möller, Merete ; Roncero, Carlos ; Stevens, Laura ; Wallhed, Sara ; van Wamel, Anneke ; Young, Jesse. / Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder : Results of the IASP study. In: Addiction. 2014 ; Vol. 109, No. 2. pp. 262-272.
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T2 - Results of the IASP study

AU - Van Emmerik-van Oortmerssen, Katelijne

AU - van de Glind, Geurt

AU - Koeter, Maarten W J

AU - Allsop, Steve

AU - Auriacombe, Marc

AU - Barta, C.

AU - Bu, Eli Torild H

AU - Burren, Yuliya

AU - Carpentier, Pieter Jan

AU - Carruthers, Susan

AU - Casas, Miguel

AU - Demetrovics, Z.

AU - Dom, Geert

AU - Faraone, Stephen V.

AU - Fatseas, Melina

AU - Franck, Johan

AU - Johnson, Brian

AU - Kapitány-Fövény, Máté

AU - Kaye, Sharlene

AU - Konstenius, Maija

AU - Levin, Frances R.

AU - Moggi, Franz

AU - Møller, Merete

AU - Ramos-Quiroga, J. Antoni

AU - Schillinger, Arild

AU - Skutle, Arvid

AU - Verspreet, Sofie

AU - van den Brink, Wim

AU - Schoevers, Robert A.

AU - Beniwal, Atul

AU - Bosma, Geert

AU - Cassar, Joanne

AU - Dahl, Therese

AU - Daigre, Constanza

AU - Debrabant, Romain

AU - Degenhardt, Louisa

AU - van der Gaag, Rutger Jan

AU - Hay, David

AU - Lossius, Kari

AU - Løvaas, Eva Karin

AU - Malivert, Marion

AU - Möller, Merete

AU - Roncero, Carlos

AU - Stevens, Laura

AU - Wallhed, Sara

AU - van Wamel, Anneke

AU - Young, Jesse

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N2 - Aims: To determine comorbidity patterns in treatment-seeking substance use disorder (SUD) patients with and without adult attention deficit hyperactivity disorder (ADHD), with an emphasis on subgroups defined by ADHD subtype, taking into account differences related to gender and primary substance of abuse. Design: Data were obtained from the cross-sectional International ADHD in Substance use disorder Prevalence (IASP) study. Setting: Forty-seven centres of SUD treatment in 10 countries. Participants: A total of 1205 treatment-seeking SUD patients. Measurements: Structured diagnostic assessments were used for all disorders: presence of ADHD was assessed with the Conners' Adult ADHD Diagnostic Interview for DSM-IV (CAADID), the presence of antisocial personality disorder (ASPD), major depression (MD) and (hypo)manic episode (HME) was assessed with the Mini International Neuropsychiatric Interview-Plus (MINI Plus), and the presence of borderline personality disorder (BPD) was assessed with the Structured Clinical Interview for DSM-IV Axis II (SCID II). Findings: The prevalence of DSM-IV adult ADHD in this SUD sample was 13.9%. ASPD [odds ratio (OR)=2.8, 95% confidence interval (CI)=1.8-4.2], BPD (OR=7.0, 95% CI=3.1-15.6 for alcohol; OR=3.4, 95% CI=1.8-6.4 for drugs), MD in patients with alcohol as primary substance of abuse (OR=4.1, 95% CI=2.1-7.8) and HME (OR=4.3, 95% CI=2.1-8.7) were all more prevalent in ADHD+ compared with ADHD- patients (P

AB - Aims: To determine comorbidity patterns in treatment-seeking substance use disorder (SUD) patients with and without adult attention deficit hyperactivity disorder (ADHD), with an emphasis on subgroups defined by ADHD subtype, taking into account differences related to gender and primary substance of abuse. Design: Data were obtained from the cross-sectional International ADHD in Substance use disorder Prevalence (IASP) study. Setting: Forty-seven centres of SUD treatment in 10 countries. Participants: A total of 1205 treatment-seeking SUD patients. Measurements: Structured diagnostic assessments were used for all disorders: presence of ADHD was assessed with the Conners' Adult ADHD Diagnostic Interview for DSM-IV (CAADID), the presence of antisocial personality disorder (ASPD), major depression (MD) and (hypo)manic episode (HME) was assessed with the Mini International Neuropsychiatric Interview-Plus (MINI Plus), and the presence of borderline personality disorder (BPD) was assessed with the Structured Clinical Interview for DSM-IV Axis II (SCID II). Findings: The prevalence of DSM-IV adult ADHD in this SUD sample was 13.9%. ASPD [odds ratio (OR)=2.8, 95% confidence interval (CI)=1.8-4.2], BPD (OR=7.0, 95% CI=3.1-15.6 for alcohol; OR=3.4, 95% CI=1.8-6.4 for drugs), MD in patients with alcohol as primary substance of abuse (OR=4.1, 95% CI=2.1-7.8) and HME (OR=4.3, 95% CI=2.1-8.7) were all more prevalent in ADHD+ compared with ADHD- patients (P

KW - ADHD

KW - Antisocial personality disorder

KW - Bipolar disorder

KW - Borderline personality disorder

KW - Comorbidity

KW - Depression

KW - Substance use disorder

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