Proteoglikánok (struktúra, funkció, szerepük májbetegségekben).

Translated title of the contribution: Proteoglycans (their structure, function and role in liver diseases)

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Proteoglycans are macromolecules containing a core protein to which glycosaminoglycan chains are covalently attached. The family contains several members with different structures and various functions. Some of them are elements of the extracellular matrix, while others are located to the cell surface playing important role in cell-cell and cell-extracellular matrix interactions. Present paper discusses the possible consequences of the alterations of proteoglycans observed in liver cirrhosis and liver tumors. It has to be emphasized however, that they are also involved in the pathomechanism of arteriosclerosis, Alzheimer-disease, immune diseases, arthritis, tumor progression and metastasis formation.

Translated title of the contributionProteoglycans (their structure, function and role in liver diseases)
Original languageHungarian
Pages (from-to)2019-2026
Number of pages8
JournalOrvosi hetilap
Volume134
Issue number37
Publication statusPublished - Sep 12 1993

ASJC Scopus subject areas

  • Medicine(all)

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