Proteins in solution

Fractal surfaces in solutions

R. Tscheliessnig, L. Pusztai

Research output: Contribution to journalArticle

Abstract

The concept of the surface of a protein in solution, as well of the interface between protein and 'bulk solution', is introduced. The experimental technique of small angle X-ray and neutron scattering is introduced and described briefly. Molecular dynamics simulation, as an appropriate computational tool for studying the hydration shell of proteins, is also discussed. The concept of protein surfaces with fractal dimensions is elaborated. We finish by exposing an experimental (using small angle X-ray scattering) and a computer simulation case study, which are meant as demonstrations of the possibilities we have at hand for investigating the delicate interfaces that connect (and divide) protein molecules and the neighboring electrolyte solution.

Original languageEnglish
Article number13803
JournalCondensed Matter Physics
Volume19
Issue number1
DOIs
Publication statusPublished - 2016

Fingerprint

fractals
proteins
scattering
hydration
neutron scattering
x rays
computerized simulation
electrolytes
molecular dynamics
molecules
simulation

Keywords

  • Protein hydration
  • Protein solution
  • Protein surface
  • Small angle scattering

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)
  • Condensed Matter Physics

Cite this

Proteins in solution : Fractal surfaces in solutions. / Tscheliessnig, R.; Pusztai, L.

In: Condensed Matter Physics, Vol. 19, No. 1, 13803, 2016.

Research output: Contribution to journalArticle

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