Abstract
Malnutrition may develop in acute pancreatitis (AP), accompanied by hypermetabolism and high nutritional requirements, and in chronic pancreatitis (CP). We measured the incidence of protein malnutrition in AP and CP by comparing different serum biomarkers of protein metabolism and inflammation. Thirty-five patients with acute (27 moderate, 8 severe), and 35 with chronic, pancreatitis were enrolled in the study. Serum transthyretin, albumin, transferrin and C-reactive protein (CRP) concentrations were measured in AP at admission, after 1 and 2 weeks of jejunal feeding, and in patients with CP at follow-up. In AP, at admission the transthyretin level was low in 74%, transferrin in 48%, and albumin in 29% of patients. In severe pancreatitis, transthyretin levels were significantly lower than in moderate forms (7.5±2.43 vs. 14.39±6.8 mg/dl, p
| Original language | English |
|---|---|
| Pages (from-to) | 1320-1324 |
| Number of pages | 5 |
| Journal | Clinical Chemistry and Laboratory Medicine |
| Volume | 40 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2002 |
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Keywords
- C-reactive protein
- Jejunal feeding
- Pancreatis
- Protein malnutrition
- Transthyretin
ASJC Scopus subject areas
- Clinical Biochemistry
Cite this
Protein status in pacreatis-Transthyretin is a sensitive biomarker of malnutrition in acute and chronic pancreatitis. / Lasztity, Natalia; Bíró, L.; Nemeth, Eva; Pap, A.; Antal, M.
In: Clinical Chemistry and Laboratory Medicine, Vol. 40, No. 12, 2002, p. 1320-1324.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Protein status in pacreatis-Transthyretin is a sensitive biomarker of malnutrition in acute and chronic pancreatitis
AU - Lasztity, Natalia
AU - Bíró, L.
AU - Nemeth, Eva
AU - Pap, A.
AU - Antal, M.
PY - 2002
Y1 - 2002
N2 - Malnutrition may develop in acute pancreatitis (AP), accompanied by hypermetabolism and high nutritional requirements, and in chronic pancreatitis (CP). We measured the incidence of protein malnutrition in AP and CP by comparing different serum biomarkers of protein metabolism and inflammation. Thirty-five patients with acute (27 moderate, 8 severe), and 35 with chronic, pancreatitis were enrolled in the study. Serum transthyretin, albumin, transferrin and C-reactive protein (CRP) concentrations were measured in AP at admission, after 1 and 2 weeks of jejunal feeding, and in patients with CP at follow-up. In AP, at admission the transthyretin level was low in 74%, transferrin in 48%, and albumin in 29% of patients. In severe pancreatitis, transthyretin levels were significantly lower than in moderate forms (7.5±2.43 vs. 14.39±6.8 mg/dl, p
AB - Malnutrition may develop in acute pancreatitis (AP), accompanied by hypermetabolism and high nutritional requirements, and in chronic pancreatitis (CP). We measured the incidence of protein malnutrition in AP and CP by comparing different serum biomarkers of protein metabolism and inflammation. Thirty-five patients with acute (27 moderate, 8 severe), and 35 with chronic, pancreatitis were enrolled in the study. Serum transthyretin, albumin, transferrin and C-reactive protein (CRP) concentrations were measured in AP at admission, after 1 and 2 weeks of jejunal feeding, and in patients with CP at follow-up. In AP, at admission the transthyretin level was low in 74%, transferrin in 48%, and albumin in 29% of patients. In severe pancreatitis, transthyretin levels were significantly lower than in moderate forms (7.5±2.43 vs. 14.39±6.8 mg/dl, p
KW - C-reactive protein
KW - Jejunal feeding
KW - Pancreatis
KW - Protein malnutrition
KW - Transthyretin
UR - http://www.scopus.com/inward/record.url?scp=0036915485&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036915485&partnerID=8YFLogxK
U2 - 10.1515/CCLM.2002.227
DO - 10.1515/CCLM.2002.227
M3 - Article
VL - 40
SP - 1320
EP - 1324
JO - Clinical Chemistry and Laboratory Medicine
JF - Clinical Chemistry and Laboratory Medicine
SN - 1434-6621
IS - 12
ER -