Protein microchips in biomedicine and biomarker discovery

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Protein microarray technology is of high recent interest, especially for generating confirmatory and complementary information for transcriptomic studies. In this paper, the advantages, technical limitations, main application fields, and some early results of protein microarrays are reviewed. Today protein microchip technology is mostly available in the form of printed glass slides, bioaffinity surfaces, and tissue microarray (TMA)-based techniques. The advantages of glass slide-based microchips are the simplicity of their application and their relatively low cost. Affinity surface-based protein chip techniques are applicable to minute amounts of starting material (

Original languageEnglish
Pages (from-to)4261-4273
Number of pages13
JournalElectrophoresis
Volume28
Issue number23
DOIs
Publication statusPublished - Dec 2007

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Protein Array Analysis
Biomarkers
Microarrays
Glass
Proteins
Technology
Membrane Proteins
Tissue
Costs and Cost Analysis
Costs

Keywords

  • Microarray
  • Microchips
  • Proteome profiling
  • Proteomics

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Protein microchips in biomedicine and biomarker discovery. / Spisák, S.; Tulassay, Z.; Molnár, B.; Guttman, A.

In: Electrophoresis, Vol. 28, No. 23, 12.2007, p. 4261-4273.

Research output: Contribution to journalArticle

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