Rosszindulatú nögyógyászati daganatos megbetegedésben szenvedö betegek K-sejt aktivitásának prospectiv vizsgálata. A sugárkezelés és mütét hatása.

Translated title of the contribution: Prospective study of K-cell activity in patients with malignant gynecologic tumors. Effect of radiation therapy

P. Siklós, I. Pete, P. Hercz, L. Ungár, Z. Vigváry, G. Ringwald, T. Bakács

Research output: Contribution to journalArticle

Abstract

K cell activity was measured in the enzyme-like kinetic model of cytotoxicity against O, Rh (D) positive erythrocytes in 127 patients with carcinoma of the uterine cervix, 55 with carcinoma of the corpus uteri and 30 with malignant tumors of the ovary. The control groups included 62 healthy age matched women and 39 patients with benign tumor of the ovary. The cytotoxic activity was measured in a number of cases before any treatment and after irradiation and surgery in patients with cervical and endometrial cancer. The target cells were obtained from the same donor. ADCC activity of cervical and ovarian tumor patients enhanced depends on the stage of the disease. K cell activity of endometrial carcinoma patients was similar to the controls. ADCC activity of patients with carcinoma of the uterine cervix was increased, with carcinoma of the uterine corpus was indicated an increasing tendency following irradiation. There was connection with the dose of the irradiation and K cell activity. On the contrary, operation did not influence ADCC activity.

Original languageHungarian
Pages (from-to)979-984
Number of pages6
JournalOrvosi Hetilap
Volume130
Issue number19
Publication statusPublished - May 7 1989

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Radiotherapy
Prospective Studies
Antibody-Dependent Cell Cytotoxicity
Carcinoma
Neoplasms
Endometrial Neoplasms
Cervix Uteri
Ovary
Uterine Cervical Neoplasms
Uterus
Erythrocytes
Tissue Donors
Control Groups
Enzymes
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Rosszindulatú nögyógyászati daganatos megbetegedésben szenvedö betegek K-sejt aktivitásának prospectiv vizsgálata. A sugárkezelés és mütét hatása. / Siklós, P.; Pete, I.; Hercz, P.; Ungár, L.; Vigváry, Z.; Ringwald, G.; Bakács, T.

In: Orvosi Hetilap, Vol. 130, No. 19, 07.05.1989, p. 979-984.

Research output: Contribution to journalArticle

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abstract = "K cell activity was measured in the enzyme-like kinetic model of cytotoxicity against O, Rh (D) positive erythrocytes in 127 patients with carcinoma of the uterine cervix, 55 with carcinoma of the corpus uteri and 30 with malignant tumors of the ovary. The control groups included 62 healthy age matched women and 39 patients with benign tumor of the ovary. The cytotoxic activity was measured in a number of cases before any treatment and after irradiation and surgery in patients with cervical and endometrial cancer. The target cells were obtained from the same donor. ADCC activity of cervical and ovarian tumor patients enhanced depends on the stage of the disease. K cell activity of endometrial carcinoma patients was similar to the controls. ADCC activity of patients with carcinoma of the uterine cervix was increased, with carcinoma of the uterine corpus was indicated an increasing tendency following irradiation. There was connection with the dose of the irradiation and K cell activity. On the contrary, operation did not influence ADCC activity.",
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