PROPHYLACTIC LIGNOCAINE AND EARLY POST‐CORONARY ARTERY OCCLUSION DYSRHYTHMIAS IN ANAESTHETIZED GREYHOUNDS

R. J. MARSHALL, J. R. PARRATT

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Lignocaine (1 mg kg−1 min−1 infused intravenously for 30 min) greatly reduced the incidence of ventricular ectopic beats that resulted from acute coronary artery ligation in anaesthetized greyhound dogs. However, the incidence of ventricular fibrillation was only slightly reduced by this treatment which caused significant myocardial depression. There is no good evidence from this study that lignocaine is a particularly effective prophylactic in acute myocardial infarction. 1980 British Pharmacological Society

Original languageEnglish
Pages (from-to)597-600
Number of pages4
JournalBritish journal of pharmacology
Volume71
Issue number2
DOIs
Publication statusPublished - Feb 1980

ASJC Scopus subject areas

  • Pharmacology

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