The effet of calcitonin was studied on the biochemical alterations following endoscopic retrograde pancreatography. Prior to ductography, 20 patients were given 100 IU of synthetic salmon calcitonin, and the results were compared to data obtained in 20 control patients who had been subjected to pancreatogrphy as usual. The increase in serum lipase and insulin levels was significantly less in the patients receiving calcitonin compared to the controls. When analysing maximum increments in serum alpha amylase and glucagon levels it could be established that, in the treated group the number of patients exhibiting pathological values following pancreatography was significantly less than in the controls. Changes in calcium and cortisol levels were not significantly different in the two groups. The observed results indicate that calcitonin pretreatment might be helpful in ameliorating the laboratory changes following endoscopic pancreatography.
- complications of ERCP
- endoscopic retrograde
- pancreas injury
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging