Properties of the perinatal steroid effects

Research output: Contribution to journalArticle

Abstract

In the rat, corticosterone adminstered in the first postnatal week produces lasting effects in the regulation of the adaptive behavioural processes. In the function of the hypophysis-adrenal cortex, divergence may be displayed prepubertally; however, this change becomes normal in adult life. The characteristic change of the exploration and passive avoidance behaviour and the modification of the corticosterone uptake of the hippocampus reflect the diminution of the function of the septo-hippocampus system. Examinations performed in the rat serve as experimental models for clinical research and call attention to the observation that glucocorticoids administered in the perinatal period influence in a lasting manner the development of the processes of the central nervous system and of the fundamental metabolic function. Beyond the review of the corticosterone effect in the newborn, a survey is also given on the peculiarities of the perinatal steroid effects.

Original languageEnglish
Pages (from-to)16-25
Number of pages10
JournalOrvoskepzes
Volume53
Issue numberSuppl. 1
Publication statusPublished - 1978

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Corticosterone
Steroids
Hippocampus
Avoidance Learning
Behavior Therapy
Adrenal Cortex
Pituitary Gland
Glucocorticoids
Theoretical Models
Central Nervous System
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Properties of the perinatal steroid effects. / Nyakas, C.

In: Orvoskepzes, Vol. 53, No. Suppl. 1, 1978, p. 16-25.

Research output: Contribution to journalArticle

Nyakas, C 1978, 'Properties of the perinatal steroid effects', Orvoskepzes, vol. 53, no. Suppl. 1, pp. 16-25.
Nyakas, C. / Properties of the perinatal steroid effects. In: Orvoskepzes. 1978 ; Vol. 53, No. Suppl. 1. pp. 16-25.
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