Properties of the adsorption equilibrium isotherms used and measured in RPLC

F. Gritti, A. Felinger, G. Guiochon

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The variety of isotherm models needed to account for the high-concentration adsorption behavior of small molecular weight compounds is surprisingly rich. For the sake of convenience, isotherms are divided into groups depending first on the sign of their curvature at very low concentrations and then on the number of their inflection points. Conventional models are easily found in this arrangement. The methods of determination of isotherms are also divided into two groups, those that give adsorption data points and those that allow only the derivation of best estimates of the coefficients of a preselected model. Finally, examples are given of the wide diversity of isotherm behavior found in RPLC and of the surprisingly large influence of the mobile phase composition on the isotherm parameters.

Original languageEnglish
JournalChromatographia
Volume60
Issue numberSUPPL.
Publication statusPublished - 2004

Fingerprint

Adsorption
Isotherms
Molecular Weight
Phase composition
Molecular weight

Keywords

  • Adsorption equilibrium
  • Column liquid chromatography
  • Frontal analysis
  • Langmuir isotherms
  • Monolithic columns

ASJC Scopus subject areas

  • Analytical Chemistry
  • Clinical Biochemistry

Cite this

Properties of the adsorption equilibrium isotherms used and measured in RPLC. / Gritti, F.; Felinger, A.; Guiochon, G.

In: Chromatographia, Vol. 60, No. SUPPL., 2004.

Research output: Contribution to journalArticle

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