Properties of mixed alkanethiol-dendrimer layers and their applications in biosensing

L. Svobodová, M. Šnejdárková, K. Tóth, R. E. Gyurcsanyi, T. Hianik

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

We studied the properties of mixed alkanethiol-dendrimer layers on a gold support and their application in biosensing. We showed that properties of glucose sensor can be modified using a different ratio of 1-hexadecanethiol (HDT) and poly(amidoamine) dendrimer of first generation (G1). The cyclic voltammetry in the presence of the redox couple, Fe(CN)6 3-/Fe(CN)64-, was used for estimating how effectively the layer blocks the redox probe's access to the electrode surface. A scanning electrochemical microscope (SECM) was used to image the resulting distribution of the organic compounds. We found that with increasing content of dendrimers, the integrity of the layers was improved.

Original languageEnglish
Pages (from-to)285-289
Number of pages5
JournalBioelectrochemistry
Volume63
Issue number1-2
DOIs
Publication statusPublished - Jun 1 2004

Keywords

  • Cyclic voltammetry
  • Dendrimers
  • Glucose oxidase
  • Hexadecanethiol
  • Scanning electrochemical microscopy

ASJC Scopus subject areas

  • Biophysics
  • Physical and Theoretical Chemistry
  • Electrochemistry

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