Promotion by sodium bromide of functional synapse formation from foreign nerves in the superior cervical ganglion of adult rat with intact preganglionic nerve supply

J. Toldi, Z. Farkas, O. Fehér, W. Dames, P. Kása, K. Gyurkovits, F. Joó, J. R. Wolff

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The possible effect of sodium bromide (NaBr) (a substance with known inhibitory action on synaptic transmission) was studied on synapse formation with foreign nerves, implanted into the superior cervical ganglion of adult rats. It was found that in spite of the presence of preganglionic nerve supply, both implanted nerves (n.XII and n.X, respectively) were enabled to establish functional synapses with the principal ganglion cells in NaBr-treated animals. In contrast, synapse formation was almost absent in ganglia of sodium chloride drinking (control) rats with intact preganglionic nerve supply. This effect of NaBr is considered to be analogous to that of GABA, whose promoting action on synaptogenesis in adult rat superior cervical ganglion has been previously described.

Original languageEnglish
Pages (from-to)19-24
Number of pages6
JournalNeuroscience Letters
Volume69
Issue number1
DOIs
Publication statusPublished - Aug 15 1986

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Superior Cervical Ganglion
Synapses
Ganglia
Hypoglossal Nerve
Sodium Chloride
Synaptic Transmission
gamma-Aminobutyric Acid
Drinking
sodium bromide

Keywords

  • adult rat
  • nerve implantation
  • sodium bromide
  • superior cervical ganglion
  • synaptogenesis

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Promotion by sodium bromide of functional synapse formation from foreign nerves in the superior cervical ganglion of adult rat with intact preganglionic nerve supply. / Toldi, J.; Farkas, Z.; Fehér, O.; Dames, W.; Kása, P.; Gyurkovits, K.; Joó, F.; Wolff, J. R.

In: Neuroscience Letters, Vol. 69, No. 1, 15.08.1986, p. 19-24.

Research output: Contribution to journalArticle

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