Prolonged Influence of a Single Neonatal Steroid (Dexamethasone) Treatment on Thymocytic Steroid Binding

Úgnes Inczefi-Gonda, G. Csaba

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Treatment of newborn rats with a single low dose of dexamethasone gave rise to lasting alteration of thymocytic receptor binding capacity. The receptors decreased markedly in number, while their affinity for the hormone was slightly increased. It appears that imprinting with a steroid changes the receptor — hormone relationship in the adult organism.

Original languageEnglish
Pages (from-to)358-360
Number of pages3
JournalExperimental and Clinical Endocrinology and Diabetes
Volume85
Issue number3
DOIs
Publication statusPublished - Jun 1985

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Keywords

  • Dexamethasone
  • Imprinting
  • Thymocytic receptor

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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