Prolinates as secondary amines in aminocarbonylation: Synthesis of N-acylated prolinates

Eszter Takács, R. Skoda-Földes, Péter Ács, Ernõ Müller, George Kokotos, L. Kollár

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Methyl prolinate and benzyl prolinate were used as secondary amine nucleophiles in palladium catalysed aminocarbonylation of iodo-aromatics and iodo-alkenes. A mixture of 2-oxo-carboxamide and carboxamide type derivatives or pure carboxamides can be obtained by using iodo-benzene or iodo-alkenes as substrates, respectively. The aminocarbonylation of iodo-alkenes in [bmim][PF6] ionic liquid was also carried out.

Original languageEnglish
Pages (from-to)62-67
Number of pages6
JournalLetters in Organic Chemistry
Volume3
Issue number1
DOIs
Publication statusPublished - Jan 2006

Fingerprint

Alkenes
Amines
Ionic Liquids
Nucleophiles
Palladium
Benzene
Derivatives
Substrates

Keywords

  • Aminocarbonylation
  • Carbon monoxide
  • Ionic liquid
  • Palladium
  • Proline

ASJC Scopus subject areas

  • Organic Chemistry
  • Biochemistry

Cite this

Prolinates as secondary amines in aminocarbonylation : Synthesis of N-acylated prolinates. / Takács, Eszter; Skoda-Földes, R.; Ács, Péter; Müller, Ernõ; Kokotos, George; Kollár, L.

In: Letters in Organic Chemistry, Vol. 3, No. 1, 01.2006, p. 62-67.

Research output: Contribution to journalArticle

Takács, Eszter ; Skoda-Földes, R. ; Ács, Péter ; Müller, Ernõ ; Kokotos, George ; Kollár, L. / Prolinates as secondary amines in aminocarbonylation : Synthesis of N-acylated prolinates. In: Letters in Organic Chemistry. 2006 ; Vol. 3, No. 1. pp. 62-67.
@article{d54ebdf6a79f4597941f1f513d64421d,
title = "Prolinates as secondary amines in aminocarbonylation: Synthesis of N-acylated prolinates",
abstract = "Methyl prolinate and benzyl prolinate were used as secondary amine nucleophiles in palladium catalysed aminocarbonylation of iodo-aromatics and iodo-alkenes. A mixture of 2-oxo-carboxamide and carboxamide type derivatives or pure carboxamides can be obtained by using iodo-benzene or iodo-alkenes as substrates, respectively. The aminocarbonylation of iodo-alkenes in [bmim][PF6] ionic liquid was also carried out.",
keywords = "Aminocarbonylation, Carbon monoxide, Ionic liquid, Palladium, Proline",
author = "Eszter Tak{\'a}cs and R. Skoda-F{\"o}ldes and P{\'e}ter {\'A}cs and Ern{\~o} M{\"u}ller and George Kokotos and L. Koll{\'a}r",
year = "2006",
month = "1",
doi = "10.2174/157017806774964431",
language = "English",
volume = "3",
pages = "62--67",
journal = "Letters in Organic Chemistry",
issn = "1570-1786",
publisher = "Bentham Science Publishers B.V.",
number = "1",

}

TY - JOUR

T1 - Prolinates as secondary amines in aminocarbonylation

T2 - Synthesis of N-acylated prolinates

AU - Takács, Eszter

AU - Skoda-Földes, R.

AU - Ács, Péter

AU - Müller, Ernõ

AU - Kokotos, George

AU - Kollár, L.

PY - 2006/1

Y1 - 2006/1

N2 - Methyl prolinate and benzyl prolinate were used as secondary amine nucleophiles in palladium catalysed aminocarbonylation of iodo-aromatics and iodo-alkenes. A mixture of 2-oxo-carboxamide and carboxamide type derivatives or pure carboxamides can be obtained by using iodo-benzene or iodo-alkenes as substrates, respectively. The aminocarbonylation of iodo-alkenes in [bmim][PF6] ionic liquid was also carried out.

AB - Methyl prolinate and benzyl prolinate were used as secondary amine nucleophiles in palladium catalysed aminocarbonylation of iodo-aromatics and iodo-alkenes. A mixture of 2-oxo-carboxamide and carboxamide type derivatives or pure carboxamides can be obtained by using iodo-benzene or iodo-alkenes as substrates, respectively. The aminocarbonylation of iodo-alkenes in [bmim][PF6] ionic liquid was also carried out.

KW - Aminocarbonylation

KW - Carbon monoxide

KW - Ionic liquid

KW - Palladium

KW - Proline

UR - http://www.scopus.com/inward/record.url?scp=33846810313&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846810313&partnerID=8YFLogxK

U2 - 10.2174/157017806774964431

DO - 10.2174/157017806774964431

M3 - Article

AN - SCOPUS:33846810313

VL - 3

SP - 62

EP - 67

JO - Letters in Organic Chemistry

JF - Letters in Organic Chemistry

SN - 1570-1786

IS - 1

ER -