Projections of primary afferent fibers to last-order premotor interneurons in the lumbar spinal cord of rats

Ildikó Wéber, Z. Puskár, Norbert Kozák, M. Antal

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

It is well established that last-order premotor interneurons in the spinal cord have crucial importance in the integration of activities generated by the spinal motor apparatus, sensory information and volleys arising from higher motor centers, indicating that they play a substantial role in spinal motor functions. Despite extensive studies, synaptic input systems of these neurons have not been investigated in detail up to now with morphological approaches. On this basis, the present experiments were aimed at the visualization of possible contacts between primary afferents and last-order premotor interneurons in the lumbar spinal cord of rats using double label neural tracing methods in light microscopy. The findings show that terminal puncta of primary afferents do establish indeed appositions on last-order premotor interneurons. From the quantitative point of view, these appositions occur, however, in limited numbers. The study also shows that last-order premotor interneurons contacted by primary afferents tend to be concentrated at the segmental level of the innervated motoneurons, and are evenly distributed along the mediolateral extent of laminae V-VI and in the dorsal portion of lamina VII.

Original languageEnglish
Pages (from-to)337-343
Number of pages7
JournalBrain Research Bulletin
Volume71
Issue number4
DOIs
Publication statusPublished - Jan 9 2007

Fingerprint

Interneurons
Spinal Cord
Motor Neurons
Microscopy
Neurons
Light

Keywords

  • Biotinylated dextran amine
  • Cholera toxin B-subunit
  • Immunocytochemistry
  • Spinal motor apparatus
  • Tract tracing

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Projections of primary afferent fibers to last-order premotor interneurons in the lumbar spinal cord of rats. / Wéber, Ildikó; Puskár, Z.; Kozák, Norbert; Antal, M.

In: Brain Research Bulletin, Vol. 71, No. 4, 09.01.2007, p. 337-343.

Research output: Contribution to journalArticle

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