Prognostic value of serum CA-125 measurements on stimulation day 1 and on the day of oocyte pickup in the prediction of IVF treatment outcome

Erik E. Hauzman, Ana R. Lagarde, Katalin Nagy, Péter Fancsovits, Ákos Murber, Gyözö Jánoki, Zoltán Papp, János Urbancsek

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: To assess whether serum levels of CA-125, a proposed marker of endometrial receptivity, are associated with pregnancy after IVF. Methods: 42 IVF pregnancies were matched with nonpregnant controls. Twenty-eight additional unmatched pregnancies were included for the comparison of pregnancy outcomes. CA-125 concentrations were measured on stimulation day 1 (SD1) and at oocyte pickup (OPU). We analyzed association between CA-125 levels and establishment of pregnancy and its outcome; correlation between CA-125 concentrations and other parameters; differences in CA-125 levels between SD1 and OPU. Results: In pregnant, but not in nonpregnant patients, CA-125 levels decreased significantly from SD1 to OPU. There was no significant difference in CA-125 levels at either time point between pregnant and nonpregnant subjects. No significant correlation was found between CA-125 levels and any other clinical or laboratory parameters. Conclusions: CA-125 measurements at the beginning of stimulation or at oocyte retrieval are not useful in predicting IVF outcome.

Original languageEnglish
Pages (from-to)265-268
Number of pages4
JournalJournal of Assisted Reproduction and Genetics
Volume22
Issue number6
DOIs
Publication statusPublished - Jun 1 2005

Keywords

  • CA-125
  • In vitro fertilization
  • Inhibin B
  • Pregnancy outcome

ASJC Scopus subject areas

  • Reproductive Medicine
  • Genetics
  • Obstetrics and Gynaecology
  • Developmental Biology
  • Genetics(clinical)

Fingerprint Dive into the research topics of 'Prognostic value of serum CA-125 measurements on stimulation day 1 and on the day of oocyte pickup in the prediction of IVF treatment outcome'. Together they form a unique fingerprint.

  • Cite this