Prognostic value of dobutamine stress echocardiography in patients with systemic hypertension and known or suspected coronary artery disease

Fabiola B. Sozzi, Abdou Elhendy, Vittoria Rizzello, Ron T. Van Domburg, M. Kertai, Eleni Vourvouri, Arend F. Schinkel, Jeroen J. Bax, Jos R. Roelandt, Don Poldermans

Research output: Contribution to journalArticle

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Abstract

Currently, there are no outcome data to suggest an incremental value of stress echocardiography in the risk stratification of patients who have hypertension after controlling for the left ventricular mass index (LVMI). This study assessed the incremental value of dobutamine stress echocardiography (DSE) for the prediction of mortality rate and cardiac events in patients who have hypertension. We studied 596 patients who had hypertension (mean age 62 ± 12 years; 382 men) and who underwent DSE for evaluation of known or suspected coronary artery disease. End points during follow-up were hard cardiac events (cardiac death and nonfatal myocardial infarction) and total mortality rate. Left ventricular hypertrophy was detected by echocardiography in 119 patients (20%). During a median follow-up of 3 years, 101 patients (17%) died (43 cardiac deaths) and 19 patients had nonfatal myocardial infarction. In an incremental multivariate analysis model, clinical predictors of hard cardiac events were age, history of congestive heart failure, and LVMI. The percentage of abnormal myocardial segments examined with DSE was incremental to the clinical model (chi square 41 vs 27, p

Original languageEnglish
Pages (from-to)733-739
Number of pages7
JournalThe American journal of cardiology
Volume94
Issue number6
DOIs
Publication statusPublished - Sep 15 2004

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Stress Echocardiography
Coronary Artery Disease
Hypertension
Myocardial Infarction
Mortality
Left Ventricular Hypertrophy
Echocardiography
Multivariate Analysis
Heart Failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Prognostic value of dobutamine stress echocardiography in patients with systemic hypertension and known or suspected coronary artery disease. / Sozzi, Fabiola B.; Elhendy, Abdou; Rizzello, Vittoria; Van Domburg, Ron T.; Kertai, M.; Vourvouri, Eleni; Schinkel, Arend F.; Bax, Jeroen J.; Roelandt, Jos R.; Poldermans, Don.

In: The American journal of cardiology, Vol. 94, No. 6, 15.09.2004, p. 733-739.

Research output: Contribution to journalArticle

Sozzi, FB, Elhendy, A, Rizzello, V, Van Domburg, RT, Kertai, M, Vourvouri, E, Schinkel, AF, Bax, JJ, Roelandt, JR & Poldermans, D 2004, 'Prognostic value of dobutamine stress echocardiography in patients with systemic hypertension and known or suspected coronary artery disease', The American journal of cardiology, vol. 94, no. 6, pp. 733-739. https://doi.org/10.1016/j.amjcard.2004.06.005
Sozzi, Fabiola B. ; Elhendy, Abdou ; Rizzello, Vittoria ; Van Domburg, Ron T. ; Kertai, M. ; Vourvouri, Eleni ; Schinkel, Arend F. ; Bax, Jeroen J. ; Roelandt, Jos R. ; Poldermans, Don. / Prognostic value of dobutamine stress echocardiography in patients with systemic hypertension and known or suspected coronary artery disease. In: The American journal of cardiology. 2004 ; Vol. 94, No. 6. pp. 733-739.
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