A malignus melanóma prognosztikus és prediktív markerei

Translated title of the contribution: Prognostic and predictive markers of malignant melanoma

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Malignant melanoma biologically can be divided into non-metastatic and metastatic forms which cannot be predicted precisely using classical clinicopathological parameters, therefore studies on novel genetic or protein markers are abundant in the literature. These studies did not result in clinically useful markers because mostly ignored the results of studies on the genetic basis of metastatic potential of malignant melanoma. Accordingly, the list of promising novel markers is short (BCL2, CDK2, MART-1, OPN). Similar to other solid malignancies, introduction of targeted therapy into clinical practice of melanoma turned the attention toward the genetic basis of resistance to chemo- and targeted therapies. These novel data could lead to the development of molecular diagnostics which can help in designing more effective therapeutic strategies of malignant melanoma.

Translated title of the contributionPrognostic and predictive markers of malignant melanoma
Original languageHungarian
Pages (from-to)79-83
Number of pages5
JournalMagyar onkologia
Volume57
Issue number2
Publication statusPublished - 2013

ASJC Scopus subject areas

  • Medicine(all)

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