Progesterone in Periplaneta americana and Neobellieria bullata adults from the procuticle phase until first progeny production

Béla Darvas, A. Székács, Adrien Fónagy, Mihály Szécsi, István Tóth

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A significant amount of progesterone-like immunoreactive material (150 ng/g) was measured by EIA in the procuticle phase of adult of both sexes of Periplaneta americana. This peak markedly decreased to 1-10 ng/g during sclerotization and was unlikely to be of dietary origin. In the case of 0- hr-old P. americana adults 96-98% of progesterone-like material was localized in the digestive tract and Malpighian tubules. In contrast, a relatively low level of progesterone-like immunoreactive material was measured in 0-hr-old Neobellieria bullata adults. Activity of 3β-HSD/isomerase converting pregnenolone to progesterone was high (22-43 fmol/mg protein/20 min) in 0- hr-old P. americana adults and significantly fell during sclerotization. High progesterone levels (13-16 ng/g), measured by HPLC-RIA, coexist with high levels of 3β-HSD/isomerase activity. Orally active human contraceptives (ethisterone, ethynodiol, ethynodiol diacetate, lynestrenol, mestranol, norgestrel, norethynodrel, tamoxifen citrate, and mifepristone) which act on mammalian steroid receptors had no significant effects on progeny production in either polytrophic or meroistic insect ovaries even at concentration of 5000 mg/kg.

Original languageEnglish
Pages (from-to)450-460
Number of pages11
JournalGeneral and Comparative Endocrinology
Volume107
Issue number3
DOIs
Publication statusPublished - Sep 1997

Fingerprint

Sarcophaga bullata
Periplaneta
Periplaneta americana
Progesterone
progesterone
sclerotization
Isomerases
isomerases
Ethisterone
Ethynodiol Diacetate
Norethynodrel
Lynestrenol
Mestranol
Norgestrel
Malpighian Tubules
pregnenolone
tamoxifen
Mifepristone
Pregnenolone
contraceptives

ASJC Scopus subject areas

  • Endocrinology

Cite this

Progesterone in Periplaneta americana and Neobellieria bullata adults from the procuticle phase until first progeny production. / Darvas, Béla; Székács, A.; Fónagy, Adrien; Szécsi, Mihály; Tóth, István.

In: General and Comparative Endocrinology, Vol. 107, No. 3, 09.1997, p. 450-460.

Research output: Contribution to journalArticle

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