Con A-stimulated leukocytes previously treated with IFN-alpha (1500 IU/ml for 4 h) were very suitable for the production of IFN-gamma with a high titre even under large-scale conditions. The properties of the IFN produced under such conditions were identical to those of IFN-gamma. The IFN-gamma produced in primed cultures showed two peaks of antiviral activity corresponding to molecular weights of 51 000 and 23 000 daltons.
|Number of pages||4|
|Journal||Acta microbiologica Hungarica|
|Publication status||Published - Dec 1 1985|
ASJC Scopus subject areas
- Microbiology (medical)