Production of high titre human interferon-gamma in primed leukocyte cultures.

V. Endrész, S. Tóth, M. Tóth

Research output: Contribution to journalArticle

Abstract

Con A-stimulated leukocytes previously treated with IFN-alpha (1500 IU/ml for 4 h) were very suitable for the production of IFN-gamma with a high titre even under large-scale conditions. The properties of the IFN produced under such conditions were identical to those of IFN-gamma. The IFN-gamma produced in primed cultures showed two peaks of antiviral activity corresponding to molecular weights of 51 000 and 23 000 daltons.

Original languageEnglish
Pages (from-to)395-398
Number of pages4
JournalActa microbiologica Hungarica
Volume32
Issue number4
Publication statusPublished - Dec 1 1985

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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