Production of drug particles using pulsed laser ablation in liquid (PLAL) technique

Eszter Nagy, Franciska Petak, Timea Szucs, Tomi Smausz, Judit Kopniczky, Rita Ambrus, Piroska Szabo-Revesz, Bela Hopp

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

According to the definition of the biopharmaceutical classification system 40% of the currently marketed drugs are poorly water-soluble, moreover 90% of drugs in development phase are also characterized as poorly water-soluble [1]. Because of this trend in drug development, pharmaceutical technology presents an important field in organic micro- and nanoparticle generation. Smaller drug particles provide higher surface to volume ratio, which indicates improved dissolution rate and transport characteristics resulting in their faster absorption and uptake by human cells [2, 3]. Pulsed laser ablation in liquid (PLAL) technique is proved to be an effective method to create inorganic and organic particles which are collected in liquid. PLAL is a simple, fast and chemical free way of creating different particles for medical applications [4, 5].

Original languageEnglish
Title of host publication2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781728104690
DOIs
Publication statusPublished - Jun 2019
Event2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019 - Munich, Germany
Duration: Jun 23 2019Jun 27 2019

Publication series

Name2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019

Conference

Conference2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019
CountryGermany
CityMunich
Period6/23/196/27/19

Fingerprint

Laser ablation
Pulsed lasers
laser ablation
pulsed lasers
drugs
Liquids
liquids
Pharmaceutical Preparations
Medical applications
Drug products
Water
Dissolution
microparticles
Cells
water
Nanoparticles
dissolving
trends
nanoparticles

ASJC Scopus subject areas

  • Spectroscopy
  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Atomic and Molecular Physics, and Optics
  • Computer Networks and Communications

Cite this

Nagy, E., Petak, F., Szucs, T., Smausz, T., Kopniczky, J., Ambrus, R., ... Hopp, B. (2019). Production of drug particles using pulsed laser ablation in liquid (PLAL) technique. In 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019 [8873211] (2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CLEOE-EQEC.2019.8873211

Production of drug particles using pulsed laser ablation in liquid (PLAL) technique. / Nagy, Eszter; Petak, Franciska; Szucs, Timea; Smausz, Tomi; Kopniczky, Judit; Ambrus, Rita; Szabo-Revesz, Piroska; Hopp, Bela.

2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. 8873211 (2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nagy, E, Petak, F, Szucs, T, Smausz, T, Kopniczky, J, Ambrus, R, Szabo-Revesz, P & Hopp, B 2019, Production of drug particles using pulsed laser ablation in liquid (PLAL) technique. in 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019., 8873211, 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019, Institute of Electrical and Electronics Engineers Inc., 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019, Munich, Germany, 6/23/19. https://doi.org/10.1109/CLEOE-EQEC.2019.8873211
Nagy E, Petak F, Szucs T, Smausz T, Kopniczky J, Ambrus R et al. Production of drug particles using pulsed laser ablation in liquid (PLAL) technique. In 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019. Institute of Electrical and Electronics Engineers Inc. 2019. 8873211. (2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019). https://doi.org/10.1109/CLEOE-EQEC.2019.8873211
Nagy, Eszter ; Petak, Franciska ; Szucs, Timea ; Smausz, Tomi ; Kopniczky, Judit ; Ambrus, Rita ; Szabo-Revesz, Piroska ; Hopp, Bela. / Production of drug particles using pulsed laser ablation in liquid (PLAL) technique. 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. (2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019).
@inproceedings{bfd7bc7c350f4bbdb0fc355cba9605a4,
title = "Production of drug particles using pulsed laser ablation in liquid (PLAL) technique",
abstract = "According to the definition of the biopharmaceutical classification system 40{\%} of the currently marketed drugs are poorly water-soluble, moreover 90{\%} of drugs in development phase are also characterized as poorly water-soluble [1]. Because of this trend in drug development, pharmaceutical technology presents an important field in organic micro- and nanoparticle generation. Smaller drug particles provide higher surface to volume ratio, which indicates improved dissolution rate and transport characteristics resulting in their faster absorption and uptake by human cells [2, 3]. Pulsed laser ablation in liquid (PLAL) technique is proved to be an effective method to create inorganic and organic particles which are collected in liquid. PLAL is a simple, fast and chemical free way of creating different particles for medical applications [4, 5].",
author = "Eszter Nagy and Franciska Petak and Timea Szucs and Tomi Smausz and Judit Kopniczky and Rita Ambrus and Piroska Szabo-Revesz and Bela Hopp",
year = "2019",
month = "6",
doi = "10.1109/CLEOE-EQEC.2019.8873211",
language = "English",
series = "2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
booktitle = "2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019",

}

TY - GEN

T1 - Production of drug particles using pulsed laser ablation in liquid (PLAL) technique

AU - Nagy, Eszter

AU - Petak, Franciska

AU - Szucs, Timea

AU - Smausz, Tomi

AU - Kopniczky, Judit

AU - Ambrus, Rita

AU - Szabo-Revesz, Piroska

AU - Hopp, Bela

PY - 2019/6

Y1 - 2019/6

N2 - According to the definition of the biopharmaceutical classification system 40% of the currently marketed drugs are poorly water-soluble, moreover 90% of drugs in development phase are also characterized as poorly water-soluble [1]. Because of this trend in drug development, pharmaceutical technology presents an important field in organic micro- and nanoparticle generation. Smaller drug particles provide higher surface to volume ratio, which indicates improved dissolution rate and transport characteristics resulting in their faster absorption and uptake by human cells [2, 3]. Pulsed laser ablation in liquid (PLAL) technique is proved to be an effective method to create inorganic and organic particles which are collected in liquid. PLAL is a simple, fast and chemical free way of creating different particles for medical applications [4, 5].

AB - According to the definition of the biopharmaceutical classification system 40% of the currently marketed drugs are poorly water-soluble, moreover 90% of drugs in development phase are also characterized as poorly water-soluble [1]. Because of this trend in drug development, pharmaceutical technology presents an important field in organic micro- and nanoparticle generation. Smaller drug particles provide higher surface to volume ratio, which indicates improved dissolution rate and transport characteristics resulting in their faster absorption and uptake by human cells [2, 3]. Pulsed laser ablation in liquid (PLAL) technique is proved to be an effective method to create inorganic and organic particles which are collected in liquid. PLAL is a simple, fast and chemical free way of creating different particles for medical applications [4, 5].

UR - http://www.scopus.com/inward/record.url?scp=85074650055&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85074650055&partnerID=8YFLogxK

U2 - 10.1109/CLEOE-EQEC.2019.8873211

DO - 10.1109/CLEOE-EQEC.2019.8873211

M3 - Conference contribution

AN - SCOPUS:85074650055

T3 - 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019

BT - 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019

PB - Institute of Electrical and Electronics Engineers Inc.

ER -