Production and antigenic effect of experimental sheep adenovirus vaccines.

V. Pálfi, S. Belák

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Adenovirus vaccines inactivated and adsorbed with different methods were prepared for the specific control of pneumoenteritis of lambs. Beta-propiolactone and formalin as inactivating agents and aluminium hydroxide gel and DEAE dextran as adjuvants were compared. Vaccines inactivated and adsorbed in different ways provoked practically the same immunological response. Seronegative lambs developed a higher level of antibodies after the administration of monovalent vaccines, than in the case of a bivalent one. It is concluded that inactivated and adsorbed adenovirus vaccines provoke a significant production of antibodies in sheep.

Original languageEnglish
Pages (from-to)135-139
Number of pages5
JournalActa Microbiologica Academiae Scientiarum Hungaricae
Volume27
Issue number2
Publication statusPublished - 1980

Fingerprint

Adenovirus Vaccines
Sheep
Propiolactone
Aluminum Hydroxide
DEAE-Dextran
Inactivated Vaccines
Formaldehyde
Antibody Formation
Vaccines
Antibodies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Production and antigenic effect of experimental sheep adenovirus vaccines. / Pálfi, V.; Belák, S.

In: Acta Microbiologica Academiae Scientiarum Hungaricae, Vol. 27, No. 2, 1980, p. 135-139.

Research output: Contribution to journalArticle

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