Processes dominating forced-flow thin-layer chromatography

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The effect of the vapor phase and other special influences on thin-layer chromatography have been investigated. Comparisons were made of the relationships of time vs. developing distance and flow rate vs. efficiency using a planar arrangement of the thin-layer. Covering the layer facilitates the reproducibility and of the migration front but the most effective optimization step for thin-layer chromatography is provided by forced-flow of the mobile phase. It is suggested that planar chromatography with a covered sorbent layer and using a pressurised solvent stream should be called forced-flow thin-layer chromtatography.

Original languageEnglish
Pages (from-to)628-632
Number of pages5
Issue number11
Publication statusPublished - Nov 1 1984



  • Dyestuffs
  • Forced-flow TLC
  • Overpressured TLC

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry
  • Organic Chemistry

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