Primary Sjogren's syndrome with secondary hyperparathyroidism

G. Pokorny, G. Karacsony, J. Hudak, M. Nagy, Z. F. Kiss, G. Mohacsi, S. Sonkodi

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Abstract

The case history of a 43-year-old woman with primary Sjogren's syndrome is presented: in 1970, xerostomia and keratoconjunctivitis sicca; in 1980, arthritis; in 1982, chronic tubulointerstitial nephritis with renal tubular acidosis and vasopressin-resistant hyposthenuria. The renal function gradually deteriorated. Chronic atrophic gastritis with vitamin B12 deficiency and chronic duodenitis with diminished disaccharidase activity in the mucosa were also diagnosed. From 1985, repeated multiple fractures of the ribs occurred, with secondary hyperparathyroidism in the background. The renal and intestinal involvement suggests that, besides the elevated parathyroid hormone level, an acquired vitamin D deficiency plays a pathogenetic role in severe osteopenia. The patient is being treated at present by haemodialysis, and subtotal parathyroidectomy and renal transplantation are planned.

Original languageEnglish
Pages (from-to)299-302
Number of pages4
JournalClinical and experimental rheumatology
Volume8
Issue number3
Publication statusPublished - Jan 1 1990

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ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

Cite this

Pokorny, G., Karacsony, G., Hudak, J., Nagy, M., Kiss, Z. F., Mohacsi, G., & Sonkodi, S. (1990). Primary Sjogren's syndrome with secondary hyperparathyroidism. Clinical and experimental rheumatology, 8(3), 299-302.