Authors present two cases of highly malignant primary signet ring cell carcinoma of the urinary bladder. One of the patients, a 63-year-old female was examined for macrohaematuria. Biopsy of the tumour showed muscle invasive cancer. Radical cystectomy and uretero-ileo-cutaneostomy were performed. The final histology of the specimen turned to be signet ring cell carcinoma. Adjuvant chemotherapy was started and one year after the operation the CT scan showed recurrence in the small pelvis. 19 months later the patient died. The other patient, a 51-year-old male was treated by transvesical prostatectomy. Histology showed signet ring cell carcinoma of bladder origin. Recurrence on the bladder neck necessitated radical cystectomy and urethero-ileo-cutaneostomy formation, complemented by adjuvant chemo- and radiotherapy. CT scan detected one year following operation recurrence, and the patient died 19 months later.
|Number of pages||4|
|Publication status||Published - Dec 1 2004|
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