Primary non-Hodgkin's lymphoma of the uterine cervix successfully treated by neoadjuvant chemotherapy: Case report

András Szánthó, János Bálega, Zsolt Csapó, Lídia Sréter, András Matolcsy, Zoltán Papp

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Introduction. Primary non-Hodgkin's lymphoma of the uterine cervix is a rare malignancy. The mainstay of therapy consists of irradiation alone or irradiation with either surgery or chemotherapy. Case report. We present the case of a 56-year-old woman diagnosed with a bulky, Ann Arbor stage IE, primary, diffuse, large B-cell non Hodgkin's lymphoma of the uterine cervix. We administered neoadjuvant chemotherapy according to CHOP protocol (cyclophosphamide, adriamycin, vincristine, and prednisone) followed by radical hysterectomy, bilateral salpingo-oophorectomy, and regional lymph node dissection. Clinical and pathological responses to the chemotherapy were complete. The patient is alive 5 years after the initial diagnosis. Conclusion. Our case emphasizes the importance of neoadjuvant chemotherapy that can provide a control of the distant microscopic metastases.

Original languageEnglish
Pages (from-to)171-174
Number of pages4
JournalGynecologic Oncology
Volume89
Issue number1
DOIs
Publication statusPublished - Apr 1 2003

Keywords

  • Cervical cancer
  • Neoadjuvant chemotherapy
  • Primary non-Hodgkin's lymphoma

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynaecology

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