BACKGROUND: The possible association between maternal appendicitis/ appendectomy during pregnancy and congenital abnormalities in the offspring was studied. CASES: Two cases with primary microcephaly were born to mothers who had complicated appendicitis owing to the delay of appendectomy resulting in abscess/ peritonitis associated with septicemia and fever in the second trimester of pregnancy. CONCLUSIONS: Delay in surgical intervention of appendicitis in pregnancy can result in maternal morbidity that may be associated with primary microcephaly in the offspring.
|Number of pages||2|
|Journal||Birth Defects Research Part A - Clinical and Molecular Teratology|
|Publication status||Published - Jul 1 2009|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Developmental Biology