Primary microcephaly in two children born to mothers with complicated appendicitis or late appendectomy during pregnancy

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3 Citations (Scopus)

Abstract

BACKGROUND: The possible association between maternal appendicitis/ appendectomy during pregnancy and congenital abnormalities in the offspring was studied. CASES: Two cases with primary microcephaly were born to mothers who had complicated appendicitis owing to the delay of appendectomy resulting in abscess/ peritonitis associated with septicemia and fever in the second trimester of pregnancy. CONCLUSIONS: Delay in surgical intervention of appendicitis in pregnancy can result in maternal morbidity that may be associated with primary microcephaly in the offspring.

Original languageEnglish
Pages (from-to)655-656
Number of pages2
JournalBirth Defects Research Part A - Clinical and Molecular Teratology
Volume85
Issue number7
DOIs
Publication statusPublished - Jul 2009

Fingerprint

Microcephaly
Appendectomy
Appendicitis
Mothers
Pregnancy
Second Pregnancy Trimester
Peritonitis
Abscess
Sepsis
Fever
Morbidity

Keywords

  • Appendectomy
  • Appendicitis
  • Microcephaly
  • Pregnancy

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health
  • Embryology

Cite this

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abstract = "BACKGROUND: The possible association between maternal appendicitis/ appendectomy during pregnancy and congenital abnormalities in the offspring was studied. CASES: Two cases with primary microcephaly were born to mothers who had complicated appendicitis owing to the delay of appendectomy resulting in abscess/ peritonitis associated with septicemia and fever in the second trimester of pregnancy. CONCLUSIONS: Delay in surgical intervention of appendicitis in pregnancy can result in maternal morbidity that may be associated with primary microcephaly in the offspring.",
keywords = "Appendectomy, Appendicitis, Microcephaly, Pregnancy",
author = "N. {\'A}cs and F. B{\'a}nhidy and E. Czeizel",
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AU - Ács, N.

AU - Bánhidy, F.

AU - Czeizel, E.

PY - 2009/7

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N2 - BACKGROUND: The possible association between maternal appendicitis/ appendectomy during pregnancy and congenital abnormalities in the offspring was studied. CASES: Two cases with primary microcephaly were born to mothers who had complicated appendicitis owing to the delay of appendectomy resulting in abscess/ peritonitis associated with septicemia and fever in the second trimester of pregnancy. CONCLUSIONS: Delay in surgical intervention of appendicitis in pregnancy can result in maternal morbidity that may be associated with primary microcephaly in the offspring.

AB - BACKGROUND: The possible association between maternal appendicitis/ appendectomy during pregnancy and congenital abnormalities in the offspring was studied. CASES: Two cases with primary microcephaly were born to mothers who had complicated appendicitis owing to the delay of appendectomy resulting in abscess/ peritonitis associated with septicemia and fever in the second trimester of pregnancy. CONCLUSIONS: Delay in surgical intervention of appendicitis in pregnancy can result in maternal morbidity that may be associated with primary microcephaly in the offspring.

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KW - Pregnancy

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