A primer haemostasis vizsgálata kevert kötöszöveti betegségben.

Translated title of the contribution: Primary hemostasis in mixed connective tissue disease

Research output: Contribution to journalArticle

Abstract

Willebrand-factor antigen level and structure analysis, ristomycin-cofactor assay, beta-thromboglobulin and thromboxane metabolite estimations were performed in 22 patients with mixed connective tissue disease. High levels of Willebrand factor antigen and activity were detected in the presence of thrombocytopenia, previous thrombotic events, pulmonary vascular lesions and in the presence of circulating antiendothelial antibodies. Increased platelet activation was documented also in antibody positive cases and in thrombocytopenia. The alterations of endothelial and platelet functions may play important role in the development of vascular complications of mixed connective tissue disease.

Original languageHungarian
Pages (from-to)2721-2722, 2725
JournalOrvosi Hetilap
Volume132
Issue number49
Publication statusPublished - Dec 8 1991

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Mixed Connective Tissue Disease
Hemostasis
Thrombocytopenia
Blood Vessels
Ristocetin
beta-Thromboglobulin
Antibodies
Thromboxanes
Platelet Activation
Blood Platelets
Lung
Von Willebrand antigen

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A primer haemostasis vizsgálata kevert kötöszöveti betegségben. / Udvardy, M.; Bodolay, E.; Szegedi, G.; Hársfalvi, J.; Boda, Z.; Rák, K.

In: Orvosi Hetilap, Vol. 132, No. 49, 08.12.1991, p. 2721-2722, 2725.

Research output: Contribution to journalArticle

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