Primary angiosarcoma of the pancreas mimicking severe acute pancreatitis - Case report

Adrienn Csiszkó, István László, Károly Palatka, Károly Gábor Szabó, Zsolt Kanyári, László Bidiga, Tamás Csonka, László Damjanovich, Zsolt Szentkereszty

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Abstract

Primary angiosarcoma of the pancreas is an extremely rare neoplasm that often mimicks severe acute pancreatitis. A 58-year-old man was admitted with clinical and laboratory signs of severe acute pancreatitis. Contrast enhanced CT scan demonstrated haemorrhagic necrotizing inflammation of the pancreas involving the pancreatic tail, splenic hilum and small bowels with multiple peripancreatic and free abdominal fluid collection. Percutaneous drainage was performed. After 13 days, laparotomy was indicated because of persistent intra-abdominal bleeding, fever and a palpable, rapidly growing mass in the left upper quadrant of the abdomen. During the operation a necrotic, haemorrhagic mass was found in the pancreatic tail; a frozen section showed malignancy, although the tumour was unresectable. Despite all conservative and surgical therapeutic attempts, the patient died within four weeks after diagnosis. Final histology justified primary angiosarcoma of the pancreas. If a patient with signs of severe acute pancreatitis has fever without elevated PCT, the presence of a malignant tumour of the pancreas should be considered.

Original languageEnglish
Pages (from-to)84-87
Number of pages4
JournalPancreatology
Volume15
Issue number1
DOIs
Publication statusPublished - Jan 1 2015

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Keywords

  • Acute necrotizing pancreatitis
  • Acute pancreatitis
  • Cancer of pancreas
  • Malignant mesenchymal tumour
  • Pancreas neoplasm
  • Sarcoma

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Gastroenterology

Cite this

Csiszkó, A., László, I., Palatka, K., Szabó, K. G., Kanyári, Z., Bidiga, L., Csonka, T., Damjanovich, L., & Szentkereszty, Z. (2015). Primary angiosarcoma of the pancreas mimicking severe acute pancreatitis - Case report. Pancreatology, 15(1), 84-87. https://doi.org/10.1016/j.pan.2014.11.008