Primary afferent fibers establish dye-coupled connections in the frog central nervous system

Timea Bácskai, C. Matesz

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Neurobiotin and Lucifer yellow, indicators of gap junctional coupling, were applied to primary afferent fibers of the frog. Following application of tracers to cervical or lumbar dorsal root fibers, a large number of labeled granule cells were detected in the corpus cerebelli, the brainstem, and the spinal cord. The vestibular nerve was found to be in dye-coupled connection with the granule cells of the auricular lobe of the cerebellum. After application of the tracers to the trigeminal nerve, elicited dye-coupled neurons located mainly in the termination area of the descending limb of the mesencephalic trigeminal nucleus. In control experiments with biotinylated dextrane amine, only primary afferent fibers were labeled. Our results suggest that gap junctional coupling exists between primary afferent fibers and their postsynaptic targets in the frog.

Original languageEnglish
Pages (from-to)317-319
Number of pages3
JournalBrain Research Bulletin
Volume57
Issue number3-4
DOIs
Publication statusPublished - Feb 3 2002

Fingerprint

Anura
Cerebellum
Coloring Agents
Central Nervous System
Tegmentum Mesencephali
Vestibular Nerve
Trigeminal Nerve
Spinal Nerve Roots
Brain Stem
Amines
Spinal Cord
Extremities
Neurons
neurobiotin
lucifer yellow

Keywords

  • Dye-coupled connections
  • Frog
  • Primary afferent fibers

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Primary afferent fibers establish dye-coupled connections in the frog central nervous system. / Bácskai, Timea; Matesz, C.

In: Brain Research Bulletin, Vol. 57, No. 3-4, 03.02.2002, p. 317-319.

Research output: Contribution to journalArticle

@article{8589ee80e9f04d6eb86450ef3727997b,
title = "Primary afferent fibers establish dye-coupled connections in the frog central nervous system",
abstract = "Neurobiotin and Lucifer yellow, indicators of gap junctional coupling, were applied to primary afferent fibers of the frog. Following application of tracers to cervical or lumbar dorsal root fibers, a large number of labeled granule cells were detected in the corpus cerebelli, the brainstem, and the spinal cord. The vestibular nerve was found to be in dye-coupled connection with the granule cells of the auricular lobe of the cerebellum. After application of the tracers to the trigeminal nerve, elicited dye-coupled neurons located mainly in the termination area of the descending limb of the mesencephalic trigeminal nucleus. In control experiments with biotinylated dextrane amine, only primary afferent fibers were labeled. Our results suggest that gap junctional coupling exists between primary afferent fibers and their postsynaptic targets in the frog.",
keywords = "Dye-coupled connections, Frog, Primary afferent fibers",
author = "Timea B{\'a}cskai and C. Matesz",
year = "2002",
month = "2",
day = "3",
doi = "10.1016/S0361-9230(01)00707-9",
language = "English",
volume = "57",
pages = "317--319",
journal = "Brain Research Bulletin",
issn = "0361-9230",
publisher = "Elsevier Inc.",
number = "3-4",

}

TY - JOUR

T1 - Primary afferent fibers establish dye-coupled connections in the frog central nervous system

AU - Bácskai, Timea

AU - Matesz, C.

PY - 2002/2/3

Y1 - 2002/2/3

N2 - Neurobiotin and Lucifer yellow, indicators of gap junctional coupling, were applied to primary afferent fibers of the frog. Following application of tracers to cervical or lumbar dorsal root fibers, a large number of labeled granule cells were detected in the corpus cerebelli, the brainstem, and the spinal cord. The vestibular nerve was found to be in dye-coupled connection with the granule cells of the auricular lobe of the cerebellum. After application of the tracers to the trigeminal nerve, elicited dye-coupled neurons located mainly in the termination area of the descending limb of the mesencephalic trigeminal nucleus. In control experiments with biotinylated dextrane amine, only primary afferent fibers were labeled. Our results suggest that gap junctional coupling exists between primary afferent fibers and their postsynaptic targets in the frog.

AB - Neurobiotin and Lucifer yellow, indicators of gap junctional coupling, were applied to primary afferent fibers of the frog. Following application of tracers to cervical or lumbar dorsal root fibers, a large number of labeled granule cells were detected in the corpus cerebelli, the brainstem, and the spinal cord. The vestibular nerve was found to be in dye-coupled connection with the granule cells of the auricular lobe of the cerebellum. After application of the tracers to the trigeminal nerve, elicited dye-coupled neurons located mainly in the termination area of the descending limb of the mesencephalic trigeminal nucleus. In control experiments with biotinylated dextrane amine, only primary afferent fibers were labeled. Our results suggest that gap junctional coupling exists between primary afferent fibers and their postsynaptic targets in the frog.

KW - Dye-coupled connections

KW - Frog

KW - Primary afferent fibers

UR - http://www.scopus.com/inward/record.url?scp=0037012262&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037012262&partnerID=8YFLogxK

U2 - 10.1016/S0361-9230(01)00707-9

DO - 10.1016/S0361-9230(01)00707-9

M3 - Article

VL - 57

SP - 317

EP - 319

JO - Brain Research Bulletin

JF - Brain Research Bulletin

SN - 0361-9230

IS - 3-4

ER -