A nyelocsovarix-vérzés megelozése és kezelése

Translated title of the contribution: Prevention and treatment of esophageal variceal bleeding

Zsuzsanna Vitális, Mária Papp, István Tornai, István Altorjay

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Portal hypertension leads to special complications, which tend to progression. Increase in the size of varices, and variceal-wall tension may cause life-threatening bleeding, which affects mortality. Therefore the reduction of portal hypertension is essential. For prevention of the first bleeding (primary prevention) beta-blockers must be given. For estimation of the effectiveness of this drug, patients should be followed. In case of inefficiency or intolerability variceal ligation or sclerotherapy can prevent bleeding. In case of acute variceal hemorrhage, hemodynamic stabilization of the patient is the first step. Transfusion if necessary, somatostatin or terlipressin should be given for reduction of portal hypertension and also endoscopic treatment of varices is mandatory. Early antibiotic administration for prophylaxis or treatment of infections is associated with a significant reduction in mortality. Up to now in absence of exact data, correction of haemostasis is suggested by the administration of fresh frozen plasma. For secondary prevention i. e. to prevent repeated bleeding beta-blockers (probably with nitrates) can be used. If necessary, drug administration should be complemented with varix ligation or sclerotherapy. In case of inefficiency TIPS implantation or liver transplantation must be considered.

Translated title of the contributionPrevention and treatment of esophageal variceal bleeding
Original languageHungarian
Pages (from-to)2455-2463
Number of pages9
JournalOrvosi hetilap
Volume147
Issue number51
Publication statusPublished - Dec 24 2006

ASJC Scopus subject areas

  • Medicine(all)

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