Prevalence of plasmid-mediated quinolone resistance determinants in Enterobacteriaceae strains isolated in North-East Italy

B. Kocsis, A. Mazzariol, E. Kocsis, R. Koncan, R. Fontana, G. Cornaglia

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Abstract

We investigated the prevalence of plasmid-mediated quinolone resistance genes in 756 clinical isolates of Enterobacteriaceae originating from Microbiology Diagnostic Laboratories of North-East Italy. Five point zero two percent of isolates carried a qnr determinant while the aac(6')-Ib-cr determinant was detected in 9.25% of isolates. We also investigated the association between the plasmid-mediated quinolone resistance and the beta-lactamase genes, and characterized the plasmids carrying these determinants of resistance.

Original languageEnglish
Pages (from-to)36-40
Number of pages5
JournalJournal of Chemotherapy
Volume25
Issue number1
DOIs
Publication statusPublished - Feb 1 2013

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Keywords

  • Enterobactriaceae
  • Fluoroquinolone resistance
  • PMQR determinants
  • QNR
  • aac(6')-ib-cr

ASJC Scopus subject areas

  • Oncology
  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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