Prevalence of GB virus C/hepatitis G virus in Hungary

M. Takács, Katalin N. Szomor, Andrea Szendroi, Ágnes Dencs, Judit Brojnás, Erzsébet Rusvai, G. Berencsi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In 1995 a new flavivirus, GB virus C/hepatitis G virus (GBV-C/HGV), was discovered. The aim of this study was to determine the prevalence of the virus in healthy persons and hepatitis patients in Hungary. The sera of 408 healthy persons older than 60 years were tested for the presence of GBV-C/HGV antibodies, and 113 were positive (28%). Eight of the 71 healthy persons younger than 60 years and twenty of the 51 sera (39%) taken from patients suffering from hepatitis of unknown origin proved to be positive for GBV-C/HGV antibodies. Ten of the 124 sera (8%) of healthy persons and 36 of the 247 sera (14.6%) of hepatitis patients proved to be positive for GBV-C/HGV RNA. Eleven PCR products were sequenced, and the sequences were found to be different from each other and from the previously published ones. However, three sequences taken from the same patient at different times were identical. These results show that GBV-C/HGV is present in Hungary and cannot be considered rare.

Original languageEnglish
Pages (from-to)283-287
Number of pages5
JournalFEMS Immunology and Medical Microbiology
Volume34
Issue number4
DOIs
Publication statusPublished - Dec 13 2002

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GB virus C
Hungary
Hepatitis
Serum
Flavivirus
Antibodies

Keywords

  • Healthy person
  • Hepatitis of unknown etiology
  • PCR
  • Sequencing

ASJC Scopus subject areas

  • Immunology
  • Microbiology
  • Infectious Diseases

Cite this

Prevalence of GB virus C/hepatitis G virus in Hungary. / Takács, M.; Szomor, Katalin N.; Szendroi, Andrea; Dencs, Ágnes; Brojnás, Judit; Rusvai, Erzsébet; Berencsi, G.

In: FEMS Immunology and Medical Microbiology, Vol. 34, No. 4, 13.12.2002, p. 283-287.

Research output: Contribution to journalArticle

Takács, M. ; Szomor, Katalin N. ; Szendroi, Andrea ; Dencs, Ágnes ; Brojnás, Judit ; Rusvai, Erzsébet ; Berencsi, G. / Prevalence of GB virus C/hepatitis G virus in Hungary. In: FEMS Immunology and Medical Microbiology. 2002 ; Vol. 34, No. 4. pp. 283-287.
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