Pressure-tuning of the secondary structures of proteins: Fourier transform infrared studies in the diamond anvil cell

László Smeller, Karel Heremans

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A self-deconvolution and fitting procedure is presented that allows the determination of pressure-induced changes in the secondary structure of proteins starting from the infrared spectrum. The method takes into account the elastic as well as the possible conformational shift of the spectral bands. Applications are presented on pressure-induced changes in bovine pancreatic trypsin inhibitor and in gramicidin incorporated into lipid bilayers.

Original languageEnglish
Pages (from-to)263-267
Number of pages5
JournalHigh Pressure Research
Volume12
Issue number4-6
DOIs
Publication statusPublished - Jan 1 1994

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Keywords

  • bovine pancreatic trypsin inhibitor
  • fitting
  • gramicidin
  • high pressure
  • infrared spectroscopy
  • self-deconvolution

ASJC Scopus subject areas

  • Condensed Matter Physics

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