Pressure distribution during negative pressure wound therapy of experimental abdominal compartment syndrome in a porcine model

Adrienn Csiszkó, Klaudia Balog, Zoltán Attila Godó, Gyula Juhász, Katalin Pető, Ádám Deák, Mariann Berhés, N. Németh, Zsolt Bodnár, Zsolt Szentkereszty

Research output: Contribution to journalArticle

Abstract

(1) Introduction: Negative pressure wound therapy (NPWT) is a frequently applied open abdomen (OA) treatment. There are only a few experimental data supporting this method and describing the optimal settings and pressure distribution in the abdominal cavity during this procedure. The aim of our study was to evaluate pressure values at different points in the abdominal cavity during NPWT in experimental abdominal compartment syndrome (ACS) animal model; (2) Methods: In this study (permission Nr. 13/2014/UDCAW), 27 Hungahib pigs (15.4–20.2 kg) were operated on. ACS was generated by implanting a plastic bag in the abdomen through mini-laparotomy and filled with 2100–3300 mL saline solution (37◦ C) to an intraabdominal pressure (IAP) of 30 mmHg. After 3 h, NPWT (Vivano Med® Abdominal Kit, Paul Hartmann AG, Germany) or a Bogota bag was applied. The NPWT group was divided into −50, −100 and −150 mmHg suction groups. Pressure distribution to the abdominal cavity was monitored at 6 different points of the abdomen via a multichannel pressure monitoring system; (3) Results: The absolute pressure levels were significantly higher above than below the protective layer. The values of the pressure were similar in the midline and laterally. Amongst the bowels, the pressure values changed periodically between 0 and −12 mmHg which might be caused by peristaltic movements; (4) Conclusions: The porcine model of the present study seems to be well applicable for investigating ACS and NPWT. It was possible to provide valuable information for clinicians. The pressure was well distributed by the protective layer to the lateral parts of the abdomen and this phenomenon did not change considerably during the therapy.

Original languageEnglish
Article number897
JournalSensors (Switzerland)
Volume18
Issue number3
DOIs
Publication statusPublished - Mar 17 2018

Fingerprint

Intra-Abdominal Hypertension
Negative-Pressure Wound Therapy
compartments
pressure distribution
Pressure distribution
therapy
Swine
Pressure
abdomen
Abdomen
Abdominal Cavity
bags
cavities
Suction
Sodium Chloride
Laparotomy
Plastics
kits
animal models
Germany

Keywords

  • Abdominal compartment syndrome
  • Intra-abdominal pressure
  • Negative ressure wound therapy
  • Open abdomen
  • Pressure sensor

ASJC Scopus subject areas

  • Analytical Chemistry
  • Atomic and Molecular Physics, and Optics
  • Biochemistry
  • Instrumentation
  • Electrical and Electronic Engineering

Cite this

Csiszkó, A., Balog, K., Godó, Z. A., Juhász, G., Pető, K., Deák, Á., ... Szentkereszty, Z. (2018). Pressure distribution during negative pressure wound therapy of experimental abdominal compartment syndrome in a porcine model. Sensors (Switzerland), 18(3), [897]. https://doi.org/10.3390/s18030897

Pressure distribution during negative pressure wound therapy of experimental abdominal compartment syndrome in a porcine model. / Csiszkó, Adrienn; Balog, Klaudia; Godó, Zoltán Attila; Juhász, Gyula; Pető, Katalin; Deák, Ádám; Berhés, Mariann; Németh, N.; Bodnár, Zsolt; Szentkereszty, Zsolt.

In: Sensors (Switzerland), Vol. 18, No. 3, 897, 17.03.2018.

Research output: Contribution to journalArticle

Csiszkó, A, Balog, K, Godó, ZA, Juhász, G, Pető, K, Deák, Á, Berhés, M, Németh, N, Bodnár, Z & Szentkereszty, Z 2018, 'Pressure distribution during negative pressure wound therapy of experimental abdominal compartment syndrome in a porcine model', Sensors (Switzerland), vol. 18, no. 3, 897. https://doi.org/10.3390/s18030897
Csiszkó, Adrienn ; Balog, Klaudia ; Godó, Zoltán Attila ; Juhász, Gyula ; Pető, Katalin ; Deák, Ádám ; Berhés, Mariann ; Németh, N. ; Bodnár, Zsolt ; Szentkereszty, Zsolt. / Pressure distribution during negative pressure wound therapy of experimental abdominal compartment syndrome in a porcine model. In: Sensors (Switzerland). 2018 ; Vol. 18, No. 3.
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abstract = "(1) Introduction: Negative pressure wound therapy (NPWT) is a frequently applied open abdomen (OA) treatment. There are only a few experimental data supporting this method and describing the optimal settings and pressure distribution in the abdominal cavity during this procedure. The aim of our study was to evaluate pressure values at different points in the abdominal cavity during NPWT in experimental abdominal compartment syndrome (ACS) animal model; (2) Methods: In this study (permission Nr. 13/2014/UDCAW), 27 Hungahib pigs (15.4–20.2 kg) were operated on. ACS was generated by implanting a plastic bag in the abdomen through mini-laparotomy and filled with 2100–3300 mL saline solution (37◦ C) to an intraabdominal pressure (IAP) of 30 mmHg. After 3 h, NPWT (Vivano Med{\circledR} Abdominal Kit, Paul Hartmann AG, Germany) or a Bogota bag was applied. The NPWT group was divided into −50, −100 and −150 mmHg suction groups. Pressure distribution to the abdominal cavity was monitored at 6 different points of the abdomen via a multichannel pressure monitoring system; (3) Results: The absolute pressure levels were significantly higher above than below the protective layer. The values of the pressure were similar in the midline and laterally. Amongst the bowels, the pressure values changed periodically between 0 and −12 mmHg which might be caused by peristaltic movements; (4) Conclusions: The porcine model of the present study seems to be well applicable for investigating ACS and NPWT. It was possible to provide valuable information for clinicians. The pressure was well distributed by the protective layer to the lateral parts of the abdomen and this phenomenon did not change considerably during the therapy.",
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AU - Pető, Katalin

AU - Deák, Ádám

AU - Berhés, Mariann

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AU - Bodnár, Zsolt

AU - Szentkereszty, Zsolt

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