Presentation and long-term follow-up of exfoliation glaucoma in Greece, Spain, Russia, and Hungary

A. G.P. Konstas, G. Hollo, Y. S. Astakhov, M. A. Teus, E. L. Akopov, J. N. Jenkins, William C. Stewart

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15 Citations (Scopus)


PURPOSE. To evaluate clinical presentation and long-term follow-up of exfoliation glaucoma in separate European population groups. METHODS. A four-center, retrospective, case series analysis in which 200 charts of patients with exfoliation glaucoma or patients with elevated intraocular pressure (IOP) associated with exfoliation syndrome in at least one eye with at least 5 years of follow-up were consecutively reviewed. RESULTS. This study found an average follow-up time of 6.0±2.1 years. Patients in Hungary and Spain statistically presented, at an older age (79 years) than Greek patients (67 years). Patients with exfoliation glaucoma in Greece and Hungary had more glaucomatous damage, had more severe glaucoma, had a higher untreated IOP (31.8 to 32.1 mmHg), and were more difficult to control, showing a greater number of changes in medicines during the follow-up period, a greater number of medicines at the end of the follow-up period, and more progression. On long-term follow-up, Greek, Russian, and Hungarian patients also had the highest mean IOP (18.8 to 20.8 mmHg) and the greatest incidence of progression (approximately 50%). Spanish patients demonstrated the lowest mean IOP (17.6±3.6 mmHg) and the lowest rate of progression (28%) during the follow-up period and the fewest number of medications per patient (0.7) to control the IOP at the end of the follow-up period. CONCLUSIONS. The severity of exfoliation glaucoma presentation and its course may differ within distinct geographic populations in Europe.

Original languageEnglish
Pages (from-to)60-66
Number of pages7
JournalEuropean Journal of Ophthalmology
Issue number1
Publication statusPublished - Jan 1 2006



  • Exfoliation glaucoma
  • Long-term follow-up
  • Presentation
  • Progression

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Konstas, A. G. P., Hollo, G., Astakhov, Y. S., Teus, M. A., Akopov, E. L., Jenkins, J. N., & Stewart, W. C. (2006). Presentation and long-term follow-up of exfoliation glaucoma in Greece, Spain, Russia, and Hungary. European Journal of Ophthalmology, 16(1), 60-66.