Presence of immunoassayable β-lipotropin in bovine brain and spinal cord: Lack of concordance with ACTH concentrations

Dorothy T. Krieger, Anthony Liotta, Toshihiro Suda, M. Palkóvits, Michael J. Brownstein

Research output: Contribution to journalArticle

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Abstract

Discrete areas of freshly obtained adult bovine brain were assayed for their content of immunoreactive β-lipotropin (β-LPH), ACTH and β-endorphin. Highest concentrations (pg/100ug protein) of β-LPH were present in hypothalamus (517 ± 81), hippocampus (218 ± 60), central grey rostral mesencephalic level, pons, striatum, and spinal cord (163-258). Lesser concentrations (49-138) were present in other parts of the limbic system, brain stem, cortex and thalamus. Immunoreactive ACTH concentrations were highest in hypothalamus (1702 ± 487) and hippocampus (210 ± 40), with markedly lesser concentrations (5-24) being present in all the other aforementioned areas. Immunoreactive β-endorphin concentrations in hypothalamus were 1990 ± 510, in hippocampus 280 ± 50.

Original languageEnglish
Pages (from-to)930-936
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume76
Issue number3
DOIs
Publication statusPublished - Jun 6 1977

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beta-Lipotropin
Endorphins
Adrenocorticotropic Hormone
Hypothalamus
Hippocampus
Brain
Spinal Cord
Limbic System
Periaqueductal Gray
Pons
Thalamus
Brain Stem
Proteins

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Presence of immunoassayable β-lipotropin in bovine brain and spinal cord : Lack of concordance with ACTH concentrations. / Krieger, Dorothy T.; Liotta, Anthony; Suda, Toshihiro; Palkóvits, M.; Brownstein, Michael J.

In: Biochemical and Biophysical Research Communications, Vol. 76, No. 3, 06.06.1977, p. 930-936.

Research output: Contribution to journalArticle

Krieger, Dorothy T. ; Liotta, Anthony ; Suda, Toshihiro ; Palkóvits, M. ; Brownstein, Michael J. / Presence of immunoassayable β-lipotropin in bovine brain and spinal cord : Lack of concordance with ACTH concentrations. In: Biochemical and Biophysical Research Communications. 1977 ; Vol. 76, No. 3. pp. 930-936.
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