Presence in and effects of pineal indoleamines at very low level of phylogeny

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The unicellular organism Tetrahymena contains serotonin and is able to take up the hormone from its mileiu. The serotonin content of the cell changes as a function of the presence of foreign exogenous hormones. This indicates a possible role of serotonin as a chemical mediator. Exogenous serotonin stimulates the RNA synthesis of Tetrahymena, and it was the only one among the hormones studied which kept the RNA level durably high. Serotonin stimulates phagocytosis and growth of Tetrahymena, and its precursors also stimulate growth. Serotonin can imprint Tetrahymena, and as a consequence of this the effect of the hormone increases in the case of further encounters. Treatment with serotonin-related molecules soon after imprinting can reduce the effect of imprinting. Melatonin can contract the pigment cells of Planaria; however, its precursors serotonin and tryptamine can do this more intensely. Both melatonin and serotonin can influenc the regeneration of Planaria, with effects which differ when different phenomena are studied. Evolutionary theories are discussed.

Original languageEnglish
Pages (from-to)627-634
Number of pages8
JournalExperientia
Volume49
Issue number8
DOIs
Publication statusPublished - Aug 1993

Fingerprint

Phylogeny
Serotonin
Tetrahymena
Hormones
Melatonin
RNA
Growth
Phagocytosis
Pigments
Regeneration
Molecules

Keywords

  • hormonal imprinting
  • melatonin
  • phylogeny
  • Planaria
  • Serotonin
  • Tetrahymena

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Presence in and effects of pineal indoleamines at very low level of phylogeny. / Csaba, G.

In: Experientia, Vol. 49, No. 8, 08.1993, p. 627-634.

Research output: Contribution to journalArticle

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