Preparative On-Line Overpressure Layer Chromatography (OPLC): A New Separation Technique for Natural Products

S. Z. Nyiredy, C. A.J. Erdelmeier, K. Dallenbach-Toelke, K. Nyiredy-Mikita, O. Sticher

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Overpressure layer chromatography (oplc) is further developed for the online preparative isolation of natural compounds. Its use is demonstrated for the rapid isolation of one or two compounds in less than 1 h as well as for the isolation of more substances from plant extracts and/or prepurified fractions which require a few hours. Depending on the separation problem, sample sizes between 50 mg and 0.5 g may be applied to 20×20 cm silica plates. Principles of the method, practical considerations, and advantages of this techique over other available methodologies are discussed.

Original languageEnglish
Pages (from-to)885-891
Number of pages7
JournalJournal of Natural Products
Volume49
Issue number5
DOIs
Publication statusPublished - Jan 1 1986

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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