Preparation of nitriles by the modification of Mitsunobu-Wilk procedure III carbon elongation of hydroxy esters

Mohammed C. Aesa, Gábor Baán, Lajos Novák, Csaba Szántay

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

An efficient one-step procedure for the conversion of hydroxy esters into the corresponding nitrile esters using triphenylphosphine (PPh3)-diethyl azodicarboxylate (DEAD) in the presence of acetone cyanohydrin is described.

Original languageEnglish
Pages (from-to)909-914
Number of pages6
JournalSynthetic Communications
Volume26
Issue number5
DOIs
Publication statusPublished - Jan 1 1996

ASJC Scopus subject areas

  • Organic Chemistry

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