Preparation of new 2,3-diphenylpropenoic acid esters - Good yields even for the more hindered Z isomers

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2 Citations (Scopus)

Abstract

The potassium salt of E- and Z-2,3-diphenylpropenoic acids prepaxed in situ could be esterified efficiently in DMSO with the appropriate alkyl halides at room temperature. In this way 10 previously undescribed esters of these acids were synthesised and characterised. Excellent yields were observed for most of the E isomers and the more hindered Z esters were also obtained in good yields, far better than those obtained applying the classical acid-catalysed esterification reaction.

Original languageEnglish
Pages (from-to)256-263
Number of pages8
JournalMolecules
Volume9
Issue number4
DOIs
Publication statusPublished - Apr 2004

Keywords

  • DMSO/KOH/alkyl halide reactant
  • Esterification of E- and Z-2,3-diphenylpropenoic acids

ASJC Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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