Preparation, characterisation and microbiological examination of Pickering nano-emulsions containing essential oils, and their effect on Streptococcus mutans biofilm treatment

Barbara Horváth, Viktória L. Balázs, Adorján Varga, Andrea Böszörményi, Béla Kocsis, Györgyi Horváth, Aleksandar Széchenyi

Research output: Contribution to journalArticle

Abstract

Essential oils (EOs) are commonly applied in mouth care products like mouthwashes, mostly as an ethanolic solution or by usage of surfactants as solubilising agents. In this study, we present a formulation for preparation of Pickering nano-emulsions (PnE) of EOs as a novel form for application of EOs in mouth care. For the preparation of PnE, we have synthesised surface-modified silica nanoparticles with a mean diameter of 20 nm, as well as we have examined the effect of EOs concentration on PnE droplet size and stability. In vitro study of their effect on the Streptococcus mutans biofilm as the main pathogen of dental health problems has been performed. We have found that EOs in the PnE form has the highest effectiveness against biofilm formation. Diffusion through the biofilm model membrane was studied to explain this observation. We have found that PnEs have a better performance in the transportation of EOs trough model membrane than the ethanolic solutions and conventional emulsions (CEs).

Original languageEnglish
Article number16611
JournalScientific reports
Volume9
Issue number1
DOIs
Publication statusPublished - Dec 1 2019

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Streptococcus mutans
Volatile Oils
Biofilms
Emulsions
Mouth
Mouthwashes
Membranes
Surface-Active Agents
Silicon Dioxide
Nanoparticles
Tooth
Health

ASJC Scopus subject areas

  • General

Cite this

Preparation, characterisation and microbiological examination of Pickering nano-emulsions containing essential oils, and their effect on Streptococcus mutans biofilm treatment. / Horváth, Barbara; Balázs, Viktória L.; Varga, Adorján; Böszörményi, Andrea; Kocsis, Béla; Horváth, Györgyi; Széchenyi, Aleksandar.

In: Scientific reports, Vol. 9, No. 1, 16611, 01.12.2019.

Research output: Contribution to journalArticle

Horváth, Barbara ; Balázs, Viktória L. ; Varga, Adorján ; Böszörményi, Andrea ; Kocsis, Béla ; Horváth, Györgyi ; Széchenyi, Aleksandar. / Preparation, characterisation and microbiological examination of Pickering nano-emulsions containing essential oils, and their effect on Streptococcus mutans biofilm treatment. In: Scientific reports. 2019 ; Vol. 9, No. 1.
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